Parathion methyl

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Parathion methyl
Parathion-methyl.svg
Methyl-parathion-from-xtal-2005-3D-balls.png
Names
IUPAC name
O,O-Dimethyl-O-p-nitrophenylphosphorothioate
Other names
Azophos, Methyl parathion, O,O-Dimethyl O-4-nitrophenyl phosphorothioate, O,O-Dimethyl-p-nitrophenylthionophosphate
Identifiers
298-00-0
ChemSpider 3987
EC Number 015-035-00-7
Jmol 3D model Interactive image
PubChem 4130
RTECS number TG0175000
UN number 2783
Properties
(CH3O)2P(S)OC6H4NO2
Molar mass 263.2 g/mol
Appearance White to tan, crystalline solid or powder[1]
Odor pungent, garlic-like[1]
Density 1.36 g/mL (20°C)[1]
Melting point 37 °C; 99 °F; 310 K[1]
Boiling point 143 °C; 289 °F; 416 K[1]
0.006% (25°C)[1]
Vapor pressure 0.00001 mmHg (20°C)[1]
Hazards
Main hazards reactive with strong oxidizers and water[1]
Lethal dose or concentration (LD, LC):
67 mg/kg (rat, dermal)[2]
10-25 mg/kg (male rat, oral)[3]
24 mg/kg (female rat, oral)[3]
US health exposure limits (NIOSH):
PEL (Permissible)
none[1]
REL (Recommended)
TWA 0.2 mg/m3 [skin][1]
IDLH (Immediate danger)
N.D.[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Parathion methyl is an organophosphate pesticide and insecticide, possessing a organothiophosphate group. It is structurally very similar to parathion-ethyl.

Applications[edit]

Parathion methyl is used as an insecticide on crops including cotton.[2]

Safety[edit]

People can be exposed to parathion methyl in the workplace by breathing it in, getting it on their skin, swallowing it, or getting it in their eyes. The Occupational Safety and Health Administration (OSHA) has not set a legal limit (permissible exposure limit) for parathion methyl exposure in the workplace. The National Institute for Occupational Safety and Health (NIOSH) has set a recommended exposure limit (REL) of 0.2 mg/m3 over an 8-hour workday.[1]

Since it is an acetylcholinesterase inhibitor, symptoms of exposure to parathion methyl include irritated eyes and skin, nausea and vomiting, abdominal pain, diarrhea, salivation, feeling weak and tired, headache, runny nose, tightness in the chest, blurry vision, pupil constriction, irregular heartbeat, muscle twitches (fasciculation), and difficulty breathing.[1]

Parathion methyl is not classified as a carcinogen by any global agency.[2]

References[edit]

  1. ^ a b c d e f g h i j k l m "NIOSH Pocket Guide to Chemical Hazards #0427". National Institute for Occupational Safety and Health (NIOSH). 
  2. ^ a b c "Skin notation profile: Methyl Parathion" (PDF). NIOSH. 
  3. ^ a b "Methyl Parathion". 1988 OSHA PEL Project Documentation. NIOSH. 28 September 2011.