Triampyzine

Triampyzine
Clinical data
Other names	(Dimethylamino)trimethylpyrazine; W-3976B; W3976-B; W-3976-B; W3976B; 3,5,6-Trimethylampyzine
Identifiers
	IUPAC name N,N,3,5,6-pentamethylpyrazin-2-amine;
CAS Number	6503-95-3 ; 7082-30-6 (sulfate);
PubChem CID	23484;
ChemSpider	21956;
UNII	OPV4883241;
ChEMBL	ChEMBL2111165;
CompTox Dashboard (EPA)	DTXSID90863888 ;
Chemical and physical data
Formula	C9H15N3
Molar mass	165.240 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=C(N=C(C(=N1)C)N(C)C)C;
	InChI InChI=1S/C9H15N3/c1-6-7(2)11-9(12(4)5)8(3)10-6/h1-5H3; Key:RKPVUWPGCFGDJO-UHFFFAOYSA-N;

Triampyzine (INNTooltip International Nonproprietary Name), also known as triampyzine sulfate (USANTooltip United States Adopted Name; developmental code name W-3976B) in the case of the sulfate salt, as (dimethylamino)trimethylpyrazine, or as 3,5,6-trimethylampyzine, is a drug described as an anticholinergic and antisecretory agent which was never marketed.^[1]^[2]^[3]^[4]^[5] It was first described in the literature by 1966.^[1]^[6] The drug is the 3,5,6-trimethylated derivative of ampyzine (W-3580B), which is also a drug and is, conversely, described as a "central stimulant".^[1]^[5]^[2]

References

^ ^a ^b ^c Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 436. ISBN 978-1-4757-2085-3. Retrieved 21 October 2024.
^ ^a ^b Milne, G.W.A. (2018). Drugs: Synonyms and Properties. Routledge Revivals. Taylor & Francis. pp. 213, 547. ISBN 978-1-351-78990-5. Retrieved 21 October 2024.
^ "TRIAMPYZINE". Inxight Drugs. Retrieved 21 October 2024.
^ Negwer, M. (1994). Organic-chemical Drugs and Their Synonyms: (an International Survey). Akademie Verlag. p. 355. ISBN 978-3-05-500156-7. Retrieved 21 October 2024.
^ ^a ^b Lednicer, D. (2009). Strategies for Organic Drug Synthesis and Design. Wiley. p. 366. ISBN 978-0-470-39959-0. Retrieved 21 October 2024.
^ Marler, E.E.J. (1967). Pharmacological and Chemical Synonyms: A Collection of Names of Drugs and Other Compounds Drawn from the Medical Literature of the World. Excerpta Medica. p. 322. Retrieved 21 October 2024.

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[Elks2014-1] Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 436. ISBN 978-1-4757-2085-3. Retrieved 21 October 2024.

[Milne2018-2] Milne, G.W.A. (2018). Drugs: Synonyms and Properties. Routledge Revivals. Taylor & Francis. pp. 213, 547. ISBN 978-1-351-78990-5. Retrieved 21 October 2024.

[InxightDrugs-3] "TRIAMPYZINE". Inxight Drugs. Retrieved 21 October 2024.

[Negwer1994-4] Negwer, M. (1994). Organic-chemical Drugs and Their Synonyms: (an International Survey). Akademie Verlag. p. 355. ISBN 978-3-05-500156-7. Retrieved 21 October 2024.

[Lednicer2009-5] Lednicer, D. (2009). Strategies for Organic Drug Synthesis and Design. Wiley. p. 366. ISBN 978-0-470-39959-0. Retrieved 21 October 2024.

[Marler1967-6] Marler, E.E.J. (1967). Pharmacological and Chemical Synonyms: A Collection of Names of Drugs and Other Compounds Drawn from the Medical Literature of the World. Excerpta Medica. p. 322. Retrieved 21 October 2024.

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