Urate-ribonucleotide phosphorylase

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urate-ribonucleotide phosphorylase
Identifiers
EC number 2.4.2.16
CAS number 9030-29-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an urate-ribonucleotide phosphorylase (EC 2.4.2.16) is an enzyme that catalyzes the chemical reaction

urate D-ribonucleotide + phosphate urate + alpha-D-ribose 1-phosphate

Thus, the two substrates of this enzyme are urate D-ribonucleotide and phosphate, whereas its two products are urate and alpha-D-ribose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is urate-ribonucleotide:phosphate alpha-D-ribosyltransferase. Other names in common use include UAR phosphorylase, and urate-ribonucleotide:phosphate D-ribosyltransferase. This enzyme participates in purine metabolism.

References[edit]

  • Laster L; Blair A (1963). "An intestinal phosphorylase for uric acid ribonucleoside". J. Biol. Chem. 238: 3348–3357. PMID 14085385.