Bone morphogenetic protein 10

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Bone morphogenetic protein 10
Identifiers
Symbols BMP10 ; MGC126783
External IDs OMIM608748 MGI1338820 HomoloGene7644 GeneCards: BMP10 Gene
Orthologs
Species Human Mouse
Entrez 27302 12154
Ensembl ENSG00000163217 ENSMUSG00000030046
UniProt O95393 Q9R229
RefSeq (mRNA) NM_014482 NM_009756
RefSeq (protein) NP_055297 NP_033886
Location (UCSC) Chr 2:
69.09 – 69.1 Mb
Chr 6:
87.43 – 87.43 Mb
PubMed search [1] [2]

Bone morphogenetic protein 10 (BMP10) is a protein that in humans is encoded by the BMP10 gene.[1][2]

BMP10 is a polypeptide belonging to the TGF-β superfamily of proteins.[2] It is a novel protein that, unlike most other BMP's, is likely to be involved in the trabeculation of the heart. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP10 is categorized as a BMP since it shares a large sequence homology with other BMP's in the TGF-β superfamily.

Further reading[edit]

References[edit]

  1. ^ "Entrez Gene: bone morphogenetic protein 10". 
  2. ^ a b Neuhaus H, Rosen V, Thies RS (February 1999). "Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily". Mech. Dev. 80 (2): 181–4. doi:10.1016/S0925-4773(98)00221-4. PMID 10072785.