Jump to content

2,3-Dichlorophenylpiperazine

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Praemonitus (talk | contribs) at 22:51, 1 November 2016 (Consolidate hatnotes). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

"DCPP" redirects here. For other uses, see DCPP (disambiguation).
2,3-Dichlorophenylpiperazine
Names
IUPAC name
1-(2,3-dichlorophenyl)piperazine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.126.497 Edit this at Wikidata
  • InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2 checkY
    Key: UDQMXYJSNNCRAS-UHFFFAOYSA-N checkY
  • InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
    Key: UDQMXYJSNNCRAS-UHFFFAOYAH
  • InChI=1/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
    Key: UDQMXYJSNNCRAS-UHFFFAOYAH
  • Clc1c(Cl)c(ccc1)N2CCNCC2
Properties
C10H12Cl2N2
Molar mass 231.12 g/mol
Appearance brown oil
Density 1.272g/cm3 °C
Melting point 242 to 244 °C (468 to 471 °F; 515 to 517 K)
Boiling point 365.1 °C (689.2 °F; 638.2 K) at 760mmHg
Hazards
Flash point 174.6 °C (346.3 °F; 447.8 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound. It is both a precursor in the synthesis of aripiprazole and one of its metabolites.[1][2] It is unknown whether 2,3-DCPP is pharmacologically active similar to its close analogue 3-chlorophenylpiperazine (mCPP).

Derivatives

See also

References

  1. ^ Leś A, Badowska-Rosłonek K, Łaszcz M, Kamieńska-Duda A, Baran P, Kaczmarek Ł (2010). "Optimization of aripiprazole synthesis". Acta Poloniae Pharmaceutica. 67 (2): 151–7. PMID 20369792.
  2. ^ Caccia S (August 2007). "N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed". Current Drug Metabolism. 8 (6): 612–22. doi:10.2174/138920007781368908. PMID 17691920.


Stub icon

This article about an organic compound is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=2,3-Dichlorophenylpiperazine&oldid=747359619"