Antrafenine

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Antrafenine
Antrafenine.svg
Clinical data
Routes of
administration
Oral
ATC code none
Legal status
Legal status
  • ℞ (Prescription only)
Pharmacokinetic data
Metabolism Hepatic
Excretion Renal
Identifiers
CAS Number 55300-30-6 YesY
PubChem (CID) 68723
DrugBank DB01419 YesY
ChemSpider 61973 YesY
UNII 21FS93Y6OE YesY
ChEMBL CHEMBL345524 YesY
Chemical and physical data
Formula C30H26F6N4O2
Molar mass 588.543 g/mol
3D model (Jmol) Interactive image
  (verify)

Antrafenine (Stakane) is a phenylpiperazine derivative drug invented in 1979.[1] It acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen,[2] but is not widely used as it has largely been replaced by newer drugs.

See also[edit]

References[edit]

  1. ^ Manoury PM, Dumas AP, Najer H, Branceni D, Prouteau M, Lefevre-Borg FM. Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates. Journal of Medicinal Chemistry. 1979 May;22(5):554-9.
  2. ^ Leatham PA, Bird HA, Wright V, Seymour D, Gordon A. A double blind study of antrafenine, naproxen and placebo in osteoarthrosis. European Journal of Rheumatology and Inflammation. 1983;6(2):209-11.