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GRIK3

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GRIK3
Identifiers
AliasesGRIK3, EAA5, GLR7, GLUR7, GluK3, GluR7a, glutamate ionotropic receptor kainate type subunit 3
External IDsOMIM: 138243; MGI: 95816; HomoloGene: 73901; GeneCards: GRIK3; OMA:GRIK3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000831

NM_001081097

RefSeq (protein)

NP_000822

NP_001074566

Location (UCSC)Chr 1: 36.8 – 37.03 MbChr 4: 125.38 – 125.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Glutamate receptor, ionotropic kainate 3 is a protein that in humans is encoded by the GRIK3 gene.[5][6]

This gene encodes a protein that belongs to the ligand-gated ionic channel family. It can coassemble with either GRIK4 or GRIK5 to form heteromeric receptors and acts as an excitatory neurotransmitter at many synapses in the central nervous system. RNA editing in the mRNA has been reported.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163873Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001985Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Puranam RS, Eubanks JH, Heinemann SF, McNamara JO (Apr 1994). "Chromosomal localization of gene for human glutamate receptor subunit-7". Somat Cell Mol Genet. 19 (6): 581–8. doi:10.1007/BF01233385. PMID 8128318. S2CID 44460126.
  6. ^ a b "Entrez Gene: GRIK3 glutamate receptor, ionotropic, kainate 3".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.