P2RX2

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P2RX2
Identifiers
Aliases P2RX2, DFNA41, P2X2, purinergic receptor P2X 2
External IDs MGI: 2665170 HomoloGene: 14251 GeneCards: P2RX2
RNA expression pattern
PBB GE P2RX2 221356 x at fs.png

PBB GE P2RX2 221372 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001164833
NM_001164834
NM_153400
NM_001310700
NM_001310701

RefSeq (protein)
Location (UCSC) Chr 12: 132.62 – 132.62 Mb Chr 5: 110.34 – 110.34 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

P2X purinoceptor 2 is a protein that in humans is encoded by the P2RX2 gene.[3][4][5]

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Lynch KJ, Touma E, Niforatos W, Kage KL, Burgard EC, van Biesen T, Kowaluk EA, Jarvis MF (Dec 1999). "Molecular and functional characterization of human P2X(2) receptors". Mol Pharmacol. 56 (6): 1171–81. PMID 10570044. 
  4. ^ Brake AJ, Wagenbach MJ, Julius D (Oct 1994). "New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor". Nature. 371 (6497): 519–23. doi:10.1038/371519a0. PMID 7523952. 
  5. ^ a b "Entrez Gene: P2RX2 purinergic receptor P2X, ligand-gated ion channel, 2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.