IL18BP

IL18BP
Identifiers
Aliases	IL18BP, IL18BPa, interleukin 18 binding protein, FVH
External IDs	OMIM: 604113; MGI: 1333800; HomoloGene: 7781; GeneCards: IL18BP; OMA:IL18BP - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	72,005,715 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	101,667,897 bp
RNA expression pattern
	Top expressed in
	spleen; ; upper lobe of left lung; ; granulocyte; ; mucosa of ileum; ; apex of heart; ; lymph node; ; right adrenal gland; ; left adrenal cortex; ; right lung; ; right adrenal cortex;
	Top expressed in
	granulocyte; ; mesenteric lymph nodes; ; seminal vesicula; ; thymus; ; mucous cell of stomach; ; tail of embryo; ; liver; ; stroma of bone marrow; ; genital tubercle; ; fetal liver hematopoietic progenitor cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	receptor antagonist activity; interleukin-18 binding;
Cellular component	extracellular region; extracellular exosome; extracellular space;
Biological process	T-helper 1 type immune response; cellular response to tumor necrosis factor; response to lipopolysaccharide; cellular response to hydrogen peroxide; extracellular negative regulation of signal transduction; interleukin-18-mediated signaling pathway; cellular response to cytokine stimulus; negative regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	10068
	16068
	ENSG00000137496
	ENSMUSG00000070427
	O95998
	Q9Z0M9
NM_001039659; NM_001039660; NM_001145055; NM_001145057; NM_005699;
	NM_173042; NM_173043; NM_173044
	NM_010531; NM_001363982; NM_001382458
NP_001034748; NP_001034749; NP_001138527; NP_001138529; NP_005690;
	NP_766630; NP_766632; NP_766632.2
	NP_034661; NP_001350911; NP_001369387
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene.^[5]^[6]

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References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137496 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070427 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M (Mar 1999). "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response". Immunity. 10 (1): 127–36. doi:10.1016/S1074-7613(00)80013-8. PMID 10023777.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

External links

IL18BP human gene location in the UCSC Genome Browser.
IL18BP human gene details in the UCSC Genome Browser.

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This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000137496 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000070427 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10023777-5] Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M (Mar 1999). "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response". Immunity. 10 (1): 127–36. doi:10.1016/S1074-7613(00)80013-8. PMID 10023777.

[entrez-6] Cite error: The named reference entrez was invoked but never defined (see the help page).

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References

Further reading

External links