S100G

S100G
Identifiers
Aliases	S100G, CABP, CABP1, CABP9K, CALB3, S100 calcium binding protein G
External IDs	OMIM: 302020; MGI: 104528; HomoloGene: 36150; GeneCards: S100G; OMA:S100G - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	16,654,670 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	161,747,595 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; Achilles tendon; ; epithelium of colon; ; corpus callosum; ; face; ; right uterine tube; ; endometrium; ; sensory nervous system; ; sensory organ;
	Top expressed in
	duodenum; ; yolk sac; ; right kidney; ; connecting tubule; ; human kidney; ; distal tubule; ; right lung lobe; ; uterus; ; left lung; ; distal convoluted tubule;
	More reference expression data
	More reference expression data
Orthologs
	795
	12309
	ENSG00000169906
	ENSMUSG00000040808
	P29377
	P97816
	NM_004057
	NM_009789
	NP_004048
	NP_033919
	Wikidata
View/Edit Human	View/Edit Mouse

S100 calcium-binding protein G (S100G) is a protein that in humans is encoded by the S100G gene.^[5]^[6]^[7]

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca²⁺ absorption by buffering Ca²⁺ in the cytoplasm and increase ATP-dependent Ca²⁺ transport in duodenal basolateral membrane vesicles.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000169906 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040808 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k". Biochem Biophys Res Commun. 185 (2): 663–9. doi:10.1016/0006-291X(92)91676-H. PMID 1610358.
^ Jeung EB, Krisinger J, Dann JL, Leung PC (Sep 1992). "Molecular cloning of the full-length cDNA encoding the human calbindin-D9k". FEBS Lett. 307 (2): 224–8. doi:10.1016/0014-5793(92)80772-9. PMID 1379540. S2CID 27787157.
^ ^a ^b "Entrez Gene: S100G S100 calcium binding protein G".

Balmain N (1991). "Calbindin-D9k. A vitamin-D-dependent, calcium-binding protein in mineralized tissues". Clin. Orthop. Relat. Res. (265): 265–76. PMID 2009668.
Fleet JC, Hock JM (1995). "Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction". J. Bone Miner. Res. 9 (10): 1565–73. doi:10.1002/jbmr.5650091009. PMID 7817802. S2CID 1687493.
Jeung EB, Leung PC, Krisinger J (1994). "The human calbindin-D9k gene. Complete structure and implications on steroid hormone regulation". J. Mol. Biol. 235 (4): 1231–8. doi:10.1006/jmbi.1994.1076. PMID 8308886.
Barley NF, Prathalingam SR, Zhi P, et al. (1999). "Factors involved in the duodenal expression of the human calbindin-D9k gene". Biochem. J. 341 (3): 491–500. doi:10.1042/0264-6021:3410491. PMC 1220384. PMID 10417310.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wang L, Klopot A, Freund JN, et al. (2004). "Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1α". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (5): G943–53. doi:10.1152/ajpgi.00121.2004. PMC 2701355. PMID 15217781.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000169906 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040808 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1610358-5] Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k". Biochem Biophys Res Commun. 185 (2): 663–9. doi:10.1016/0006-291X(92)91676-H. PMID 1610358.

[pmid1379540-6] Jeung EB, Krisinger J, Dann JL, Leung PC (Sep 1992). "Molecular cloning of the full-length cDNA encoding the human calbindin-D9k". FEBS Lett. 307 (2): 224–8. doi:10.1016/0014-5793(92)80772-9. PMID 1379540. S2CID 27787157.

[entrez-7] "Entrez Gene: S100G S100 calcium binding protein G".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

References

Further reading