CAMK2D

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Calcium/calmodulin-dependent protein kinase II delta
Protein CAMK2D PDB 2VN9.png
Rendering based on PDB 2VN9.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols CAMK2D ; CAMKD
External IDs OMIM607708 MGI1341265 HomoloGene55561 ChEMBL: 2801 GeneCards: CAMK2D Gene
EC number 2.7.11.17
Orthologs
Species Human Mouse
Entrez 817 108058
Ensembl ENSG00000145349 ENSMUSG00000053819
UniProt Q13557 Q6PHZ2
RefSeq (mRNA) NM_001221 NM_001025438
RefSeq (protein) NP_001212 NP_001020609
Location (UCSC) Chr 4:
114.37 – 114.68 Mb
Chr 3:
126.6 – 126.84 Mb
PubMed search [1] [2]

Calcium/calmodulin-dependent protein kinase type II delta chain is an enzyme that in humans is encoded by the CAMK2D gene.[1]

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca2+/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Four alternatively spliced transcript variants that encode three different isoforms have been characterized to date. Distinct isoforms of this chain have different expression patterns.[1]

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