4-Keto-PCP

4-Keto-PCP
Identifiers
	IUPAC name 4-phenyl-4-piperidin-1-ylcyclohexan-1-one;
CAS Number	65620-13-5;
PubChem CID	13306756;
CompTox Dashboard (EPA)	DTXSID601336915 ;
Chemical and physical data
Formula	C17H23NO
Molar mass	257.377 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CCN(CC1)C2(CCC(=O)CC2)C3=CC=CC=C3;
	InChI InChI=1S/C17H23NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8H,2,5-6,9-14H2; Key:HBVUBDNRZWJTSB-UHFFFAOYSA-N;

4-Keto-PCP is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It has potency in between that of ketamine and phencyclidine but with somewhat more sedating effects in animal studies.^[1]

References

^ Ortiz DM, Custodio RJ, Abiero A, Botanas CJ, Sayson LV, Kim M, Lee HJ, Kim HJ, Jeong Y, Yoon S, Lee YS, Cheong JH (November 2020). "The dopaminergic alterations induced by 4-F-PCP and 4-Keto-PCP may enhance their drug-induced rewarding and reinforcing effects: Implications for abuse". Addiction Biology. 26 (4): e12981. doi:10.1111/adb.12981. PMID 33135332. S2CID 226234538.

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