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Mabuterol

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Mabuterol
Names
IUPAC name
(RS)-1-[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH mabuterol
UNII
  • InChI=1S/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3 checkY
    Key: JSJCTEKTBOKRST-UHFFFAOYSA-N checkY
  • InChI=1/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3
    Key: JSJCTEKTBOKRST-UHFFFAOYAW
  • Clc1cc(cc(c1N)C(F)(F)F)C(O)CNC(C)(C)C
Properties
C13H18ClF3N2O
Molar mass 310.74 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Mabuterol is a selective β2 adrenoreceptor agonist.[1][2]

References

  1. ^ Osada, E; Murai, T; Ishizaka, Y; Sanai, K (1984). "Pharmacological studies of mabuterol, a new selective beta 2-stimulant. II: Effects on the cardiovascular system and smooth muscle organs". Arzneimittel-Forschung. 34 (11A): 1641–51. PMID 6152157.
  2. ^ Akahane K, Furukawa Y, Ogiwara Y, Haniuda M, Chiba S (July 1989). "Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog". Br. J. Pharmacol. 97 (3): 709–16. doi:10.1111/j.1476-5381.1989.tb12007.x. PMC 1854580. PMID 2474351.