Lysosomal trafficking regulator

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lysosomal trafficking regulator
Symbol LYST
Alt. symbols CHS1
Entrez 1130
HUGO 1968
OMIM 606897
RefSeq NM_000081
UniProt Q99698
Other data
Locus Chr. 1 q42.1-42.2

Lysosomal trafficking regulator is a vesicular transport protein associated with Chédiak-Higashi syndrome.

In melanocytic cells LYST gene expression may be regulated by MITF.[1]


  1. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 

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