COPB2

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COPB2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases COPB2, beta'-COP, coatomer protein complex subunit beta 2
External IDs MGI: 1354962 HomoloGene: 3499 GeneCards: COPB2
RNA expression pattern
PBB GE COPB2 201098 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004766

NM_015827

RefSeq (protein)

NP_004757

NP_056642.1
NP_056642

Location (UCSC) Chr 3: 139.36 – 139.39 Mb Chr 9: 98.56 – 98.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Coatomer subunit beta' is a protein that in humans is encoded by the COPB2 gene.[3][4]

Function[edit]

The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM][4]

Interactions[edit]

COPB2 has been shown to interact with:

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ De Baere E, Speleman F, Van Roy N, De Paepe A, Messiaen L (February 1999). "Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization". Cytogenet Cell Genet. 82 (3–4): 226–7. doi:10.1159/000015107. PMID 9858824. 
  4. ^ a b "Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)". 
  5. ^ Eugster A, Frigerio G, Dale M, Duden R (August 2000). "COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP". EMBO J. 19 (15): 3905–17. doi:10.1093/emboj/19.15.3905. PMC 306616Freely accessible. PMID 10921873. 
  6. ^ Lowe M, Kreis TE (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. PMID 8940050. 
  7. ^ England K, Ashford D, Kidd D, Rumsby M (June 2002). "PKC epsilon is associated with myosin IIA and actin in fibroblasts". Cell. Signal. 14 (6): 529–36. doi:10.1016/s0898-6568(01)00277-7. PMID 11897493. 
  8. ^ Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM (September 2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport". Mol. Biol. Cell. 11 (9): 3155–68. doi:10.1091/mbc.11.9.3155. PMC 14982Freely accessible. PMID 10982407. 

External links[edit]

Further reading[edit]