Masoprocol

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Masoprocol
Masoprocol.svg
Clinical data
Trade names Actinex
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy
category
  • US: B (No risk in non-human studies)
Routes of
administration
Topical
ATC code
Pharmacokinetic data
Bioavailability Very low
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard 100.044.172
Chemical and physical data
Formula C18H22O4
Molar mass 302.365 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

Also called nordihydroguaiaretic acid, NDGA, and actinex.

Mechanism[edit]

Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.

It is a lipoxygenase inhibitor.[1]

References[edit]

  1. ^ "Masoprocol decreases rat lipolytic activity by decreasing the phosphorylation of HSL". Am. J. Physiol. Endocrinol. Metab. 279 (3): E593–600. September 2000. PMID 10950827. 

External links[edit]