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Phosphomevalonate kinase

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Phosphomevalonate kinase
Identifiers
EC no.2.7.4.2
CAS no.9026-46-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
Phosphomevalonate kinase
Identifiers
SymbolPMVK
NCBI gene10654
HGNC9141
OMIM607622
RefSeqNM_006556
UniProtQ15126
Other data
EC number2.7.4.2
LocusChr. 1 p13-q23
Search for
StructuresSwiss-model
DomainsInterPro

Phosphomevalonate kinase is an enzyme (EC 2.7.4.2) in the mevalonate pathway.[1][2][3]

Mevalonate pathway

References

  1. ^ Bloch, K.; Chaykin, S.; Phillips, A.H.; de Waard, A. (1959). "Mevalonic acid pyrophosphate and isopentenyl pyrophosphate". J. Biol. Chem. 234: 2595–2604. PMID 13801508.
  2. ^ Henning, U.; Möslein, E.M.; Lynen, F. (1959). "Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase". Arch. Biochem. Biophys. 83: 259–267. doi:10.1016/0003-9861(59)90031-1. PMID 13662013.
  3. ^ Levy, G.B.; Popják, G. (1960). "Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver". Biochem. J. 75: 417–428. doi:10.1042/bj0750417. PMC 1204488. PMID 14416398.