1-Aminocyclopropane-1-carboxylic acid

1-Aminocyclopropane-1-carboxylic acid
Names
	Other names 1-Aminocyclopropanecarboxylic acid
Identifiers
CAS Number	22059-21-8 ;
3D model (JSmol)	: Interactive image; Interactive image;
Abbreviations	ACC
ChEBI	CHEBI:58360 ;
ChEMBL	ChEMBL265325 ;
ChemSpider	520 ;
DrugBank	DB02085 ;
ECHA InfoCard	100.108.227
KEGG	C01234 ;
PubChem CID	535;
CompTox Dashboard (EPA)	DTXSID9039577 ;
	InChI InChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7) Key: PAJPWUMXBYXFCZ-UHFFFAOYSA-N ; InChI=1/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7) Key: PAJPWUMXBYXFCZ-UHFFFAOYAF;
	SMILES : C(O)(=O)C1(CC1)(N); O=C(O)C1(N)CC1;
Properties
Chemical formula	C4H7NO2
Molar mass	101.1 c
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

1-Aminocyclopropane-1-carboxylic acid (ACC) is a disubstituted cyclic α-amino acid in which a three-membered cyclopropane ring is fused to the C_α atom of the amino acid.

ACC plays an important role in the biosynthesis of the plant hormone ethylene.^[2]^[3] It is synthesized by the enzyme ACC synthase ( EC 4.4.1.14) from methionine and converted to ethylene by ACC oxidase (EC 1.14.17.4).^[4]

ACC is also an exogenous partial agonist of the mammalian NMDA receptor.^[5]

References

^ Caspi R, Foerster H, Fulcher CA, Hopkinson R, Ingraham J, Kaipa P, Krummenacker M, Paley S, Pick J, Rhee SY, Tissier C, Zhang P, Karp PD (2006). "MetaCyc: a multiorganism database of metabolic pathways and enzymes". Nucleic Acids Res. 34 (Database issue): D511–6. doi:10.1093/nar/gkj128. PMC 1347490. PMID 16381923.
^ Yang S, Hoffman N (1984). "Ethylene biosynthesis and its regulation in higher plants". Annu. Rev. Plant Physiol. 35: 155–189. doi:10.1146/annurev.pp.35.060184.001103.
^ Kende H (1993). "Ethylene biosynthesis". Annu. Rev. Plant Physiol. 44: 283–307. doi:10.1146/annurev.pp.44.060193.001435.
^ Kende H (1989). "Enzymes of Ethylene Biosynthesis". Plant Physiol. 91 (1): 1–4. doi:10.1104/pp.91.1.1. PMC 1061940. PMID 16666977.
^ Inanobe A, Furukawa H, Gouaux E (2005). "Mechanism of partial agonist action at the NR1 subunit of NMDA receptors". Neuron. 47 (1): 71–84. doi:10.1016/j.neuron.2005.05.022. PMID 15996549.

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

[pmid16381923-1] Caspi R, Foerster H, Fulcher CA, Hopkinson R, Ingraham J, Kaipa P, Krummenacker M, Paley S, Pick J, Rhee SY, Tissier C, Zhang P, Karp PD (2006). "MetaCyc: a multiorganism database of metabolic pathways and enzymes". Nucleic Acids Res. 34 (Database issue): D511–6. doi:10.1093/nar/gkj128. PMC 1347490. PMID 16381923.

[Yang_1984-2] Yang S, Hoffman N (1984). "Ethylene biosynthesis and its regulation in higher plants". Annu. Rev. Plant Physiol. 35: 155–189. doi:10.1146/annurev.pp.35.060184.001103.

[Kende_1993-3] Kende H (1993). "Ethylene biosynthesis". Annu. Rev. Plant Physiol. 44: 283–307. doi:10.1146/annurev.pp.44.060193.001435.

[Kende_1989-4] Kende H (1989). "Enzymes of Ethylene Biosynthesis". Plant Physiol. 91 (1): 1–4. doi:10.1104/pp.91.1.1. PMC 1061940. PMID 16666977.

[pmid15996549-5] Inanobe A, Furukawa H, Gouaux E (2005). "Mechanism of partial agonist action at the NR1 subunit of NMDA receptors". Neuron. 47 (1): 71–84. doi:10.1016/j.neuron.2005.05.022. PMID 15996549.

[1]

[2]

[3]

[4]

[5]