Haplogroup R (mtDNA)
Haplogroup R | |
---|---|
Possible time of origin | 66.8±14.2 kya [1] |
Possible place of origin | South Asia[2][3] Southeast Asia[4] |
Ancestor | N |
Descendants | R0, R1, R1b, R2'JT, R3, R5, R6'7, R8, R9, R11'B, R12'21, R14, R22, R23, R30, R31, P, U |
Defining mutations | 12705, 16223[5] |
Haplogroup R is a widely distributed human mitochondrial DNA (mtDNA) haplogroup. Haplogroup R is associated with the peopling of Eurasia after about 70,000 years ago, and is distributed in modern populations throughout the world outside of sub-Saharan Africa.[6]
Haplogroup R is a descendant of the macro-haplogroup N. Among the R clade's descendant haplogroups are B, U (and thus K), F, R0 (and thus HV, H, and V), and JT (the ancestral haplogroup of J and T).
Origin
Soares et al. (2009) estimate the age of haplogroup R to 66.8±14.2 kya (95% CI),[1] that is, between roughly 80,000 and 50,000 years ago, with a most likely age near about 65,000 years.
This is consistent with an emergence in the course of the Coastal Migration out of East Africa to West, South and Southeast Asia.[3] It has been suggested that the early lineage of haplogroups M, N and R along the coastal route during the period of roughly 70,000 to 60,000 years ago.[7]
Haplogroup R has wide diversity and antiquity in the indigenous population of South Asia. Tribes and castes of Western and Southern India show higher diversity than the other regions, possibly suggesting their autochthonous status.[2] Larruga et al. (2017) found mtDNA R spread out to Eurasia and Australia from a core area along the Southeast Asian coast.[6] The Ust'-Ishim man fossil of Siberia, dated ca. 45,000 years old, belongs to haplogroup R* (formerly classified as U*).[8][9]
Distribution
Haplogroup R and its descendants are distributed all over Australasia, Americas, Southeast Asia, South Asia, Central Asia, West Asia, East Asia, Europe, North Africa and Horn of Africa.
The basal R* clade is found among the Soqotri (1.2%), as well as in Northeast Africa (1.5%), the Middle East (0.8%), the Near East (0.8%), and the Arabian peninsula (0.3%).[10]
Haplogroup R has also been observed among ancient Egyptian mummies excavated at the Abusir el-Meleq archaeological site in Middle Egypt, which date from the Pre-Ptolemaic/late New Kingdom, Ptolemaic, and Roman periods.[11]
Subclade R2 was observed in the remains of a Neolithic human from western Iran in Tepe Abdul Hosein.[12]
Subclades
- Haplogroup R
- R0 or pre-HV
- R0a or (preHV)1: Occurs commonly in the Arabian peninsula, with its highest frequency observed among the Soqotri.[13] Moderate frequencies found in North Africa, the Horn of Africa, and Central Asia.
- HV: It is a west Eurasian haplogroup mainly found throughout the Middle East, including Iran.[14] It is also found in North Africa, Central Asia and South Asia.
- V: Found at moderately low frequencies around Europe; the highest frequency is in the Sami people 40%.[15]
- HV1: Mainly in the Middle East.[16]
- HV2: Mainly in South Asia.[14]
- HV3: Mainly in Eastern Europe.[17]
- H: In West Eurasia. It is the most common mtDNA haplogroup in Europe.
- R1
- R1a* (3337): Found in Brahmins from Uttar Pradesh (India).[7] Also in Adygei people (Caucasus).
- R1a1: Found in Northwest Caucasian people like Kabardins and Adygei people. Observed in eastern European populations like northwestern Russians and Poles.[17]
- R1b: Observed in an Eastern hunter gatherer from Karelia, Russia, dated to 5500 BCE.[18]
- R1b1: Observed in Bulgaria, Armenia (including an ancient specimen), and India
- R1b1a: Observed in Uyghurs
- R1b1b: Observed in Finland (including Finland Swedes)
- R1b2
- R1b2a: Observed in Yakuts
- R1b2b: Observed in Uyghurs
- R1b1: Observed in Bulgaria, Armenia (including an ancient specimen), and India
- pre-JT or R2'JT
- R2: Found mainly in Balochistan (Pakistan).[14]
- JT
- J: The highest frequency is in the Near East (12%), 21% in Saudi Arabia.[16] J declines towards Europe at 11%, Caucasus 8%, North Africa 6% and becomes practically missing in East Asia.[19]
- T: The highest frequency is in the Caspian region (Caucasus, Northern Iran, Turkmenistan).[14] It is important in Europe (almost 10%),[20] Middle East, Central Asia, Pakistan and North Africa. Small frequency in the Horn of Africa and India.
- R3: Found in Armenia.[21] Also observed in an ancient individual from Hungary, dating to 7000 years ago[22]
- R5: Widely spread in the Indian subcontinent. Specially in Madhya Pradesh (India) at 17%.[23]
- R6'7 (16362) The most important presence is among Austroasiatic language-speakers from India (10%).[24]
- R8: The highest frequency occurs towards East India, especially within Orissa (12%), and it is found among the Austroasiatic tribes (Munda speakers). It is also present in low frequency among the Dravidian and Indo-European speaking family [26]
- R8a: Found mainly in Orissa and Andhra Pradesh (India).
- R8b: In Orissa, Gujarat, Andhra Pradesh (India).
- R9 (16304)
- R9b: It appears mostly in Southeast Asia.[27] Found all over Indonesia, in Indochina, Malaysia, in Aboriginal Malays like Semelai at 28% and Temuan 21%.[28]
- (249d)
- R9c: All over the Malay Archipelago and Taiwan. Mainly in Batak (Palawan) at 58%,[29] the Tsou of Taiwan (22.9%),[30] and Alor (Indonesia) at 11%.[31]
- F: Fairly common in East Asia and Southeast Asia. Higher frequencies occur in some areas like Nicobar at 50% and Arunachal Pradesh 31% (India),[23] and Shors people from Siberia at 44%.[32] There is also an important frequency in Taiwanese aborigines, Guangdong (China), Maluku (Indonesia), Thailand and Vietnam.
- R11'B (16189)
- R11: Found in China, mainly in Lahu people from Yunnan at 12.5%.[33] Also in Japan, Chams,[34] and Rajasthan (India).
- B
- B4: It is found often in East Asia, Southeast Asia, Polynesia, Melanesia, Micronesia, Madagascar and Indigenous peoples of the Americas.
- B5: Spread in East Asia and Southeast Asia.
- R24: Found in Philippines.[35]
- R12'21
- R14: Found in Papua New Guinea[38] and in Austronesian speakers of East Timor and Lembata.[39]
- R22 or R12: Very frequent in the Shompen (10/29 = 34.5%).[40] Elsewhere found mainly in south-central Indonesia (11.4% Mataram, 8.0% Waingapu, 7.3% Bali, 1.9% Borneo) and in Cham of Bình Thuận, Vietnam (7/168 = 4.2%),[41] with singleton or sporadic occurrences in Thailand, Sumatra, Java, Sulawesi, and Alor.[31]
- R23: Small clade found in Bali and Sumba (Indonesia).[31]
- R30
- R30a: Found in Andhra Pradesh, Uttar Pradesh (India), in the Tharu people from Nepal[42] and Sinhalese people from Sri Lanka.[24]
- R30b: Found in Punjab.[24]
- R30* (1598, 16189): Found in Punjab, Nepal and Japan.[42]
- R31
- R31a: In Brahmins from Uttar Pradesh[7] and Rajputs from Rajasthan (India).[24]
- R31b: In Reddys from Andhra Pradesh (India).[7]
- R32
- R0 or pre-HV
Found in Mauritius
- P: It is characteristic of Sahul. Found in Philippines and East Indonesia.
- (16176)
- P1: Widespread in Melanesia. Higher frequencies occur in Papua New Guinea.[43] Also found in Maluku, Nusa Tenggara and Polynesia.[44]
- P2'10
- P2: In Melanesia,[43] specially in New Guinea and New Caledonia.
- P10: Found in Philippines.[35]
- P9 (or AuE): In Aboriginal Australians from the central region.[45]
- P3: In Australia and Melanesia.[43]
- P4: In Australia and Melanesia.[46]
- (16176)
- U
- U1: It appears mostly in the Middle East and Caucasus. Found from India to the Mediterranean and to the rest of Europe.[47]
- U5: Approximately 11% of total Europeans and 10% of European-Americans. The highest frequency is in the Sami people.[15]
- U6: It is common in North Africa and the Horn of Africa, especially in the Maghreb.[48] Highest frequencies of the subclade occur among Algerian Berbers (29%)[49] and Egyptian Copts (27.6%).[50] U6 has also been found among Iberomaurusian specimens dating from the Epipaleolithic at the Taforalt prehistoric site.[51]
- U2'3'4'7'8'9 (1811): Widely spread in West Eurasia and the Indian subcontinent.
- U8
- P: It is characteristic of Sahul. Found in Philippines and East Indonesia.
Tree
This phylogenetic tree of haplogroup R subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[5] and subsequent published research.
- R
- R0 (formerly pre-HV)
- R1
- R1a
- R1a1
- R1a1a
- R1a1
- R1a
- R2'JT
- R5
- R5a
- R5a1
- R5a1a
- R5a2
- R5a2a
- R5a2b
- R5a2b1
- R5a2b2
- R5a2b3
- R5a2b4
- R5a1
- R5a
- R6'7
- R6
- R6a
- R6a1
- R6a1a
- R6a1
- R6a
- R7
- R7a
- R7a1
- R7a1a
- R7a1b
- R7a1b1
- R7a1b2
- R7a1
- R7b
- R7b1
- R7b1a
- R7b1
- R7a
- R6
- R8 - India
- R8a - Sri Lanka
- R8a1
- R8a1a
- R8a1a1
- R8a1a2
- R8a1a3 - South Africa, Norway
- R8a1b
- R8a1a
- R8a2
- R8a1
- R8b
- R8b1
- R8b2
- R8a - Sri Lanka
- (16304)
- R9
- R9b - Cambodia, Thailand (Lao Isan in Ubon Ratchathani Province and Roi Et Province),[52] Guinea
- R9b1 - China, Uyghur, Thailand (Mon in Central Thailand, Thai in Western Thailand), Laos (Lao in Vientiane[52]), Vietnam (La Hủ), Denmark
- R9b1a
- R9b1a1 - Philippines (Mamanwa)
- R9b1a1a - China, Thailand (Karen and Thai Lue in Northern Thailand, Lao Isan in Roi Et Province,[52] Thai in Central Thailand and Eastern Thailand), Cambodia (Banteay Meanchey), Malaysia (Semelai, aboriginal Malay), Singapore, Indonesia (Tengger, Palembang, Padang, Manado), Vietnam (Giarai)
- R9b1a2 - Taiwan (Tsou), Thailand (Lao Isan in Loei Province, Thai in Western Thailand)
- R9b1a2a - China (Han from Tai'an, etc.), Vietnam (Tay, etc.), Russia (Tubalar)
- R9b1a2b - China, Taiwan (Minnan, Hakka), Vietnam (Tay), Thailand (Khon Mueang from Chiang Rai Province, Tai Khuen from Northern Thailand)
- R9b1a3 - Thailand, China (Han, Dai), Vietnam (Dao, Nùng, etc.), Kazakhstan
- R9b1a1 - Philippines (Mamanwa)
- R9b1b - China, Vietnam, Cambodia (Siem Reap), Thailand (Khon Mueang from Chiang Mai Province, Tai Yuan from Central Thailand, Mon from Northern Thailand)
- R9b1a
- R9b2 - Thailand, Cambodia, Vietnam
- R9b1 - China, Uyghur, Thailand (Mon in Central Thailand, Thai in Western Thailand), Laos (Lao in Vientiane[52]), Vietnam (La Hủ), Denmark
- R9c - China (Barghut from Hulun Buir), Taiwan
- R9c1
- R9c1a - Philippines, Indonesia, Taiwan (Makatao), Thailand (Khon Mueang from Chiang Rai Province)
- R9c1b
- R9c1b1 - China (Han), Vietnam (Kinh, Dao), Thailand (Tai Dam in Kanchanaburi Province, Khon Mueang in Mae Hong Son Province, Tai Yuan in Northern Thailand, Thai Lue in Northern Thailand), Myanmar
- R9c1b2 - Thailand (Khon Mueang in Chiang Rai Province), Taiwan (Makatao, etc.), Philippines (Ifugao, Bugkalot), East Timor
- R9c1
- F
- R22
- R9b - Cambodia, Thailand (Lao Isan in Ubon Ratchathani Province and Roi Et Province),[52] Guinea
- R9
- R11'B (16189)
- R11
- R11a
- B
- R24
- R11
- R12'21
- R12
- R21
- R22
- R14
- R23
- R30
- R30a
- R30b
- R30b1
- R31
- R31a
- R31a1
- R31b
- R31a
- R32
- P
- U
References
- ^ a b Soares, Pedro; Ermini, Luca; Thomson, Noel; Mormina, Maru; Rito, Teresa; Röhl, Arne; Salas, Antonio; Oppenheimer, Stephen; MacAulay, Vincent (2009). "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". The American Journal of Human Genetics. 84 (6): 740–59. doi:10.1016/j.ajhg.2009.05.001. PMC 2694979. PMID 19500773.
- ^ a b Maji, Suvendu; Krithika, S.; Vasul, T.S. (2008). "Distribution of Mitochondrial DNA Macrohaplogroup N in India with Special Reference to Haplogroup R and its Sub-Haplogroup U" (PDF). International Journal of Human Genetics. 8 (1–2): 85–96. doi:10.1080/09723757.2008.11886022.
- ^ a b c Karmin, Monika (2005). Human mitochondrial DNA haplogroup R in India: dissecting the phylogenetic tree of South Asian-specific lineages (M.Sc. Thesis). University of Tartu. hdl:10062/567. OCLC 692161090.[page needed]
- ^ Larruga, Jose M (23 May 2017). "Carriers of mitochondrial DNA macrohaplogroup R colonized Eurasia and Australasia from a southeast Asia core area". BMC Evolutionary Biology. 17 (1): 115. doi:10.1186/s12862-017-0964-5. PMC 5442693. PMID 28535779.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b Van Oven, Mannis; Kayser, Manfred (2009). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–94. doi:10.1002/humu.20921. PMID 18853457.
- ^ a b Larruga, Jose M (23 May 2017). "Carriers of mitochondrial DNA macrohaplogroup R colonized Eurasia and Australasia from a southeast Asia core area". BMC Evolutionary Biology. 17 (1): 115. doi:10.1186/s12862-017-0964-5. PMC 5442693. PMID 28535779.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b c d Palanichamy, Malliya Gounder; Sun, Chang; Agrawal, Suraksha; Bandelt, Hans-Jürgen; Kong, Qing-Peng; Khan, Faisal; Wang, Cheng-Ye; Chaudhuri, Tapas Kumar; Palla, Venkatramana (2004). "Phylogeny of Mitochondrial DNA Macrohaplogroup N in India, Based on Complete Sequencing: Implications for the Peopling of South Asia". The American Journal of Human Genetics. 75 (6): 966–78. doi:10.1086/425871. PMC 1182158. PMID 15467980.
- ^ Marrero, Patricia; Abu-Amero, Khaled K; Larruga, Jose M; Cabrera, Vicente M (2016). "Carriers of human mitochondrial DNA macrohaplogroup M colonized India from southeastern Asia". BMC Evolutionary Biology. 16 (1): 246. doi:10.1186/s12862-016-0816-8. PMC 5105315. PMID 27832758.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Larruga, Jose M; Marrero, Patricia; Abu-Amero, Khaled K; Golubenko, Maria V; Cabrera, Vicente M (2017). "Carriers of mitochondrial DNA macrohaplogroup R colonized Eurasia and Australasia from a southeast Asia core area". BMC Evolutionary Biology. 17 (1): 115. doi:10.1186/s12862-017-0964-5. PMC 5442693. PMID 28535779.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Černý, Viktor; et al. (2009). "Out of Arabia—the settlement of island Soqotra as revealed by mitochondrial and Y chromosome genetic diversity" (PDF). American Journal of Physical Anthropology. 138 (4): 439–447. doi:10.1002/ajpa.20960. PMID 19012329. Archived from the original (PDF) on 6 October 2016. Retrieved 13 June 2016.
- ^ Schuenemann, Verena J.; et al. (2017). "Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods". Nature Communications. 8: 15694. Bibcode:2017NatCo...815694S. doi:10.1038/ncomms15694. PMC 5459999. PMID 28556824.
- ^ Broushaki, Farnaz; Thomas, Mark G.; Link, Vivian; López, Saioa; van Dorp, Lucy; Kirsanow, Karola; Hofmanová, Zuzana; Diekmann, Yoan; Cassidy, Lara M.; Díez-del-Molino, David; Kousathanas, Athanasios; Sell, Christian; Robson, Harry K.; Martiniano, Rui; Blöcher, Jens; Scheu, Amelie; Kreutzer, Susanne; Bollongino, Ruth; Bobo, Dean; Davoudi, Hossein; Munoz, Olivia; Currat, Mathias; Abdi, Kamyar; Biglari, Fereidoun; Craig, Oliver E.; Bradley, Daniel G.; Shennan, Stephen; Veeramah, Krishna R.; Mashkour, Marjan; Wegmann, Daniel; Hellenthal, Garrett; Burger, Joachim (29 July 2016). "Early Neolithic genomes from the eastern Fertile Crescent" (PDF). Science. 353 (6298): 499–503. Bibcode:2016Sci...353..499B. doi:10.1126/science.aaf7943. PMC 5113750. PMID 27417496. Retrieved 17 November 2019.
- ^ Non, Amy. "ANALYSES OF GENETIC DATA WITHIN AN INTERDISCIPLINARY FRAMEWORK TO INVESTIGATE RECENT HUMAN EVOLUTIONARY HISTORY AND COMPLEX DISEASE" (PDF). University of Florida. Retrieved 22 April 2016.
- ^ a b c d Quintana-Murci, Lluís; Chaix, Raphaëlle; Wells, R. Spencer; Behar, Doron M.; Sayar, Hamid; Scozzari, Rosaria; Rengo, Chiara; Al-Zahery, Nadia; Semino, Ornella (2004). "Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor". The American Journal of Human Genetics. 74 (5): 827–45. doi:10.1086/383236. PMC 1181978. PMID 15077202.
- ^ a b Helgason, Agnar; Hickey, Eileen; Goodacre, Sara; Bosnes, Vidar; Stefánsson, Kári; Ward, Ryk; Sykes, Bryan (2001). "MtDNA and the Islands of the North Atlantic: Estimating the Proportions of Norse and Gaelic Ancestry". The American Journal of Human Genetics. 68 (3): 723–37. doi:10.1086/318785. PMC 1274484. PMID 11179019.
- ^ a b Abu-Amero, Khaled K; Larruga, José M; Cabrera, Vicente M; González, Ana M (2008). "Mitochondrial DNA structure in the Arabian Peninsula". BMC Evolutionary Biology. 8: 45. doi:10.1186/1471-2148-8-45. PMC 2268671. PMID 18269758.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b Malyarchuk, B.; Grzybowski, T.; Derenko, M.; Perkova, M.; Vanecek, T.; Lazur, J.; Gomolcak, P.; Tsybovsky, I. (2008). "Mitochondrial DNA Phylogeny in Eastern and Western Slavs". Molecular Biology and Evolution. 25 (8): 1651–8. doi:10.1093/molbev/msn114. PMID 18477584.
- ^ Mittnik, Alissa; Wang, Chuan-Chao; Pfrengle, Saskia; Daubaras, Mantas; Zariņa, Gunita; Hallgren, Fredrik; Allmäe, Raili; Khartanovich, Valery; Moiseyev, Vyacheslav; Tõrv, Mari; Furtwängler, Anja (2018-01-30). "The genetic prehistory of the Baltic Sea region". Nature Communications. 9 (1): 442. Bibcode:2018NatCo...9..442M. doi:10.1038/s41467-018-02825-9. ISSN 2041-1723. PMC 5789860. PMID 29382937.
- ^ Serk, Piia (2004). Human Mitochondrial DNA Haplogroup J in Europe and Near East (M.Sc. Thesis). Estonia: University of Tartu. hdl:10062/777. OCLC 692161303.[page needed]
- ^ oxfordancestors.com Maternal Ancestry Archived 2017-07-15 at the Wayback Machine
- ^ Mannis van Oven's PhyloTree.org – mtDNA subtree R Archived 2009-06-13 at the Wayback Machine
- ^ Fu, Qiaomei; Posth, Cosimo; Hajdinjak, Mateja; Petr, Martin; Mallick, Swapan; Fernandes, Daniel; Furtwängler, Anja; Haak, Wolfgang; Meyer, Matthias; Mittnik, Alissa; Nickel, Birgit (June 2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. ISSN 1476-4687. PMC 4943878. PMID 27135931.
- ^ a b c Metspalu, Mait; Kivisild, Toomas; Metspalu, Ene; Parik, Jüri; Hudjashov, Georgi; Kaldma, Katrin; Serk, Piia; Karmin, Monika; Behar, Doron M; Gilbert, M Thomas P; Endicott, Phillip; Mastana, Sarabjit; Papiha, Surinder S; Skorecki, Karl; Torroni, Antonio; Villems, Richard (2004). "Most of the extant mtDNA boundaries in south and southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans". BMC Genetics. 5: 26. doi:10.1186/1471-2156-5-26. PMC 516768. PMID 15339343.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b c d e f g Chaubey, Gyaneshwer; Karmin, Monika; Metspalu, Ene; Metspalu, Mait; Selvi-Rani, Deepa; Singh, Vijay; Parik, Jüri; Solnik, Anu; Naidu, B Prathap; Kumar, Ajay; Adarsh, Niharika; Mallick, Chandana; Trivedi, Bhargav; Prakash, Swami; Reddy, Ramesh; Shukla, Parul; Bhagat, Sanjana; Verma, Swati; Vasnik, Samiksha; Khan, Imran; Barwa, Anshu; Sahoo, Dipti; Sharma, Archana; Rashid, Mamoon; Chandra, Vishal; Reddy, Alla G; Torroni, Antonio; Foley, Robert A; Thangaraj, Kumarasamy; Singh, Lalji (2008). "Phylogeography of mtDNA haplogroup R7 in the Indian peninsula". BMC Evolutionary Biology. 8: 227. doi:10.1186/1471-2148-8-227. PMC 2529308. PMID 18680585.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b c "Figure 4. The frequency distribution of R7a and R7b clades in Indian subcontinent". in Chaubey, Gyaneshwer; Karmin, Monika; Metspalu, Ene; Metspalu, Mait; Selvi-Rani, Deepa; Singh, Vijay; Parik, Jüri; Solnik, Anu; Naidu, B Prathap; Kumar, Ajay; Adarsh, Niharika; Mallick, Chandana; Trivedi, Bhargav; Prakash, Swami; Reddy, Ramesh; Shukla, Parul; Bhagat, Sanjana; Verma, Swati; Vasnik, Samiksha; Khan, Imran; Barwa, Anshu; Sahoo, Dipti; Sharma, Archana; Rashid, Mamoon; Chandra, Vishal; Reddy, Alla G; Torroni, Antonio; Foley, Robert A; Thangaraj, Kumarasamy; Singh, Lalji (2008). "Phylogeography of mtDNA haplogroup R7 in the Indian peninsula". BMC Evolutionary Biology. 8: 227. doi:10.1186/1471-2148-8-227. PMC 2529308. PMID 18680585.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Figure 4 in Thangaraj, Kumarasamy; Nandan, Amrita; Sharma, Vishwas; Sharma, Varun Kumar; Eaaswarkhanth, Muthukrishnan; Patra, Pradeep Kumar; Singh, Sandhya; Rekha, Sashi; Dua, Monika; et al. (2009). Ahmed, Niyaz (ed.). "Deep Rooting In-Situ Expansion of mtDNA Haplogroup R8 in South Asia". PLoS ONE. 4 (8): e6545. Bibcode:2009PLoSO...4.6545T. doi:10.1371/journal.pone.0006545. PMC 2718812. PMID 19662095.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Ian Logan 2009, Haplogrupo R9b, Mitochondrial DNA Site
- ^ a b Hill, C.; Soares, P.; Mormina, M.; MacAulay, V.; Meehan, W.; Blackburn, J.; Clarke, D.; Raja, J. M.; Ismail, P. (2006). "Phylogeography and Ethnogenesis of Aboriginal Southeast Asians". Molecular Biology and Evolution. 23 (12): 2480–91. doi:10.1093/molbev/msl124. PMID 16982817.
- ^ Scholes, Clarissa; Siddle, Katherine; Ducourneau, Axel; Crivellaro, Federica; Järve, Mari; Rootsi, Siiri; Bellatti, Maggie; Tabbada, Kristina; Mormina, Maru (2011). "Genetic diversity and evidence for population admixture in Batak Negritos from Palawan". American Journal of Physical Anthropology. 146 (1): 62–72. doi:10.1002/ajpa.21544. PMID 21796613.
- ^ Albert Min-Shan Ko, Chung-Yu Chen, Qiaomei Fu, et al. (2014), "Early Austronesians: Into and Out Of Taiwan." The American Journal of Human Genetics 94, 426–436, March 6, 2014.
- ^ a b c Hill, Catherine; Soares, Pedro; Mormina, Maru; MacAulay, Vincent; Clarke, Dougie; Blumbach, Petya B.; Vizuete-Forster, Matthieu; Forster, Peter; Bulbeck, David; Oppenheimer, Stephen; Richards, Martin (2007). "A Mitochondrial Stratigraphy for Island Southeast Asia". The American Journal of Human Genetics. 80 (1): 29–43. doi:10.1086/510412. PMC 1876738. PMID 17160892.
- ^ Derenko, Miroslava; Malyarchuk, Boris; Grzybowski, Tomasz; Denisova, Galina; Dambueva, Irina; Perkova, Maria; Dorzhu, Choduraa; Luzina, Faina; Lee, Hong Kyu (2007). "Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations". The American Journal of Human Genetics. 81 (5): 1025–41. doi:10.1086/522933. PMC 2265662. PMID 17924343.
- ^ Tanaka, M.; Cabrera, VM; González, AM; Larruga, JM; Takeyasu, T; Fuku, N; Guo, LJ; Hirose, R; Fujita, Y (2004). "Mitochondrial Genome Variation in Eastern Asia and the Peopling of Japan". Genome Research. 14 (10a): 1832–50. doi:10.1101/gr.2286304. PMC 524407. PMID 15466285.
- ^ He, J-D; Peng, M-S; Quang, HH; Dang, KP; Trieu, AV; et al. (2012). "Patrilineal Perspective on the Austronesian Diffusion in Mainland Southeast Asia". PLoS ONE. 7 (5): e36437. Bibcode:2012PLoSO...736437H. doi:10.1371/journal.pone.0036437. PMC 3346718. PMID 22586471.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b Tabbada, K. A.; Trejaut, J.; Loo, J.-H.; Chen, Y.-M.; Lin, M.; Mirazon-Lahr, M.; Kivisild, T.; De Ungria, M. C. A. (2009). "Philippine Mitochondrial DNA Diversity: A Populated Viaduct between Taiwan and Indonesia?". Molecular Biology and Evolution. 27 (1): 21–31. doi:10.1093/molbev/msp215. PMID 19755666.
- ^ Pierson, M. J.; Martinez-Arias, R; Holland, BR; Gemmell, NJ; Hurles, ME; Penny, D (2006). "Deciphering Past Human Population Movements in Oceania: Provably Optimal Trees of 127 mtDNA Genomes". Molecular Biology and Evolution. 23 (10): 1966–75. doi:10.1093/molbev/msl063. PMC 2674580. PMID 16855009.
- ^ Kutanan, Wibhu; Kampuansai, Jatupol; Changmai, Piya; et al. (2018). "Contrasting maternal and paternal genetic variation of hunter-gatherer groups in Thailand". Scientific Reports. 8: 1536. Bibcode:2018NatSR...8.1536K. doi:10.1038/s41598-018-20020-0. PMC 5784115. PMID 29367746.
- ^ Haplogroup R14, Ian Logan's Mitochondrial DNA Site
- ^ Mona, S.; Grunz, K. E.; Brauer, S.; Pakendorf, B.; Castri, L.; Sudoyo, H.; Marzuki, S.; Barnes, R. H.; Schmidtke, J. (2009). "Genetic Admixture History of Eastern Indonesia as Revealed by Y-Chromosome and Mitochondrial DNA Analysis". Molecular Biology and Evolution. 26 (8): 1865–77. doi:10.1093/molbev/msp097. PMID 19414523.
- ^ Trivedi, Rajni; Sitalaximi, T.; Banerjee, Jheelam; et al. (2006). "Molecular insights into the origins of the Shompen, a declining population of the Nicobar archipelago". J Hum Genet. 51 (3): 217–226. doi:10.1007/s10038-005-0349-2. PMID 16453062.
- ^ Peng, Min-Sheng; Ho Quang, Huy; Pham Dang, Khoa; et al. (2010). "Tracing the Austronesian Footprint in Mainland Southeast Asia: A Perspective from Mitochondrial DNA". Mol. Biol. Evol. 27 (10): 2417–2430. doi:10.1093/molbev/msq131. PMID 20513740.
- ^ a b Fornarino, Simona; Pala, Maria; Battaglia, Vincenza; Maranta, Ramona; Achilli, Alessandro; Modiano, Guido; Torroni, Antonio; Semino, Ornella; Santachiara-Benerecetti, Silvana A (2009). "Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): A reservoir of genetic variation". BMC Evolutionary Biology. 9: 154. doi:10.1186/1471-2148-9-154. PMC 2720951. PMID 19573232.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b c Friedlaender, J.; Schurr, T; Gentz, F; Koki, G; Friedlaender, F; Horvat, G; Babb, P; Cerchio, S; Kaestle, F (2005). "Expanding Southwest Pacific Mitochondrial Haplogroups P and Q". Molecular Biology and Evolution. 22 (6): 1506–17. doi:10.1093/molbev/msi142. PMID 15814828.
- ^ Kayser, M.; Brauer, S; Cordaux, R; Casto, A; Lao, O; Zhivotovsky, LA; Moyse-Faurie, C; Rutledge, RB; Schiefenhoevel, W (2006). "Melanesian and Asian Origins of Polynesians: MtDNA and Y Chromosome Gradients Across the Pacific". Molecular Biology and Evolution. 23 (11): 2234–44. doi:10.1093/molbev/msl093. PMID 16923821.
- ^ Harding, Rosalind 2006, Gene tree analyses of Aboriginal Australians. Archived 2009-09-20 at the Wayback Machine University of Oxford
- ^ Hudjashov, G.; Kivisild, T.; Underhill, P. A.; Endicott, P.; Sanchez, J. J.; Lin, A. A.; Shen, P.; Oefner, P.; Renfrew, C.; et al. (2007). "Revealing the prehistoric settlement of Australia by Y chromosome and mtDNA analysis". Proceedings of the National Academy of Sciences. 104 (21): 8726–30. Bibcode:2007PNAS..104.8726H. doi:10.1073/pnas.0702928104. JSTOR 25427741. PMC 1885570. PMID 17496137.
- ^ mtDNA Haplogroup U1a page at cagetti.com[unreliable source?]
- ^ Karima Fadhlaoui-Zid; Laura Rodríguez-Botigué; Nejib Naoui; Amel Benammar-Elgaaied; Francesc Calafell; David Comas (May 2011). "Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley" (PDF). American Journal of Physical Anthropology. 145 (1): 107–117. doi:10.1002/ajpa.21472. hdl:10261/42802. PMID 21312180. Retrieved 22 April 2016.
- ^ Maca-Meyer, Nicole; González, Ana M; Pestano, José; Flores, Carlos; Larruga, José M; Cabrera, Vicente M (2003). "Mitochondrial DNA transit between West Asia and North Africa inferred from U6 phylogeography". BMC Genetics. 4: 15. doi:10.1186/1471-2156-4-15. PMC 270091. PMID 14563219.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Mohamed, Hisham Yousif Hassan. "Genetic Patterns of Y-chromosome and Mitochondrial DNA Variation, with Implications to the Peopling of the Sudan" (PDF). University of Khartoum. Retrieved 22 April 2016.
- ^ Bernard Secher; Rosa Fregel; José M Larruga; Vicente M Cabrera; Phillip Endicott; José J Pestano; Ana M González (2014). "The history of the North African mitochondrial DNA haplogroup U6 gene flow into the African, Eurasian and American continents". BMC Evolutionary Biology. 14: 109. doi:10.1186/1471-2148-14-109. PMC 4062890. PMID 24885141.
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: CS1 maint: unflagged free DOI (link) - ^ a b c Cite error: The named reference
Kutanan2016
was invoked but never defined (see the help page).
External links
![](http://upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png)
- Mannis van Oven's PhyloTree.org – mtDNA subtree R
- Ian Logan's Mitochondrial DNA Site
Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
Mitochondrial Eve (L) | |||||||||||||||||||||||||||||||||||||||
L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
M | N | ||||||||||||||||||||||||||||||||||||||
CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
HV | JT | K | |||||||||||||||||||||||||||||||||||||
H | V | J | T |