List of adaptins
Adaptins are proteins that mediate the formation of vesicles by clathrin-coated pits, through interaction with membrane-bound receptors. There are several types of adaptin, each related to a different group of such receptors.
Adaptins cluster to form the AP2 complex.
The Adaptin complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma):
- complex 1
- complex 2
- complex 3
- complex 4
- complex 5
A diagram of the 5 complexes is shown here
- Mattera R, Guardia CM, Sidhu SS, Bonifacino JS, J Biol Chem. 2015 Dec 25;290(52):30736-49. "Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex.". ncbi.nlm.nih.gov. American Society for Biochemistry and Molecular Biology. Retrieved 17 April 2017.
- Alberts, Johnson, Lewis, Raff, Roberts, Walter: Molecular Biology of the Cell, 4th edition (2002), Garland Science.
- Hirst J, D. Barlow L, Francisco GC, Sahlender DA, Seaman MNJ, Dacks JB, et al. (2011) The Fifth Adaptor Protein Complex. PLoS Biol 9(10): e1001170. doi:10.1371/journal.pbio.1001170
|This biology article is a stub. You can help Wikipedia by expanding it.|
|This article includes a list of related items that share the same name (or similar names).|