Fenoprofen

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Fenoprofen
Fenoprofen2DACS.svg
Fenoprofen-3D-balls.png
Clinical data
AHFS/Drugs.com Monograph
MedlinePlus a681026
Pregnancy
category
  • US: D (Evidence of risk)
  • C
Routes of
administration
Oral
ATC code
Legal status
Legal status
Pharmacokinetic data
Metabolism Major urinary metabolites are fenoprofen glucuronide and 4′-hydroxyfenoprofen glucuronide.
Biological half-life 3 hours
Excretion Renal (~90%)
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.047.356
Chemical and physical data
Formula C15H14O3
Molar mass 242.26986 g/mol
3D model (Jmol)
  (verify)

Fenoprofen is a non-steroidal anti-inflammatory drug. Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. Fenoprofen is marketed in the USA as Nalfon.

As of 2015 the cost for a typical month of medication in the United States is 50 to 100 USD.[1]

Pharmacology[edit]

Decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.

Contraindications[edit]

History of significantly impaired renal function; patients with known hypersensitivity to any component of the product; patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs; treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.

Drug interactions[edit]

Laboratory test interactions[edit]

False elevation in free and total serum T 3 as measured by Amerlex-M kit.

Brand names[edit]

References[edit]

  1. ^ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 8X. ISBN 9781284057560. 

External links[edit]