Masoprocol
Appearance
Clinical data | |
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Trade names | Actinex |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
Routes of administration | Topical |
ATC code | |
Pharmacokinetic data | |
Bioavailability | Very low |
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CAS Number | |
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IUPHAR/BPS | |
DrugBank | |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.044.172 |
Chemical and physical data | |
Formula | C18H22O4 |
Molar mass | 302.365 g/mol g·mol−1 |
3D model (JSmol) | |
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Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.
Also called nordihydroguaiaretic acid, NDGA, and actinex.
Mechanism
Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.
It is a lipoxygenase inhibitor.[1]
References
External links
- MedlinePlus Drug Information
- Actinex entry in the public domain NCI Cancer Dictionary