May 6, 2492: Belgian astronomerJean Meeus asserts that the orbits of all eight planets and Pluto will be within the same 90° arc of the Solar System. The last time this is believed to have occurred was on February 1, 949.
Parts of the final Star Trek: Voyager episode, "Endgame", takes place in the year 2404. The future Kathryn Janeway brought technology from that year to the year 2378 when she traveled back in time to help her crew get home 16 years earlier.
DC Comics super-hero team the Justice Society of America uses a time-ray to travel from 1942 to 2442, in an attempt to get a Bomb Defense Formula which can produce a bomb-proof shield to protect America from bombing raids, feeling it will be perfected by then. It is shown by now humanity has colonised other planets.
The JSA foe Landor travelled back 500 yrs from the year 2446, as by his time the world is much more peacful. He is intelligent enough to make weapons out of ordinary devices, creating a gun out of a flashlight, for example. At the end of the story, Green Lantern restores him to his proper time.
DC Comics superhero Booster Gold was born in the 25th century, as well as supervillain Reverse-Flash, who gets his superspeed powers using a time capsule buried in the 20th century containing a costume of the Flash.
In the Australian TV series The Girl from Tomorrow, Tulista visits the year 2500 and comes back with Silverthorn who is from the year 2500.
The events of the original computer game in the StarCraft series begin on December 12, 2499, crossing over into 2500.
In Russ Manning's series Magnus, Robot Fighter, in 2500, a robotic repair ship crashes on a planet around the star malev and suffers severe damage. This leads to the creation of Malev-6, a malevolent computer that fills the entire planet.
In 2500, oceans cover the Earth except for a few natural & man-made atolls – and remnants of humanity. A new breed of human, called Mariner, helps a woman and a child in their quest for a legendary location, Dryland – Waterworld, 1995
The game Face of Mankind takes place in a persistent world where it the year is currently in the 2400s.
In the game StarCraft 2, James "Jim" Raynor was born on August 8, 2470. This was revealed on the Collectors Edition Dog Tag.
Parts of the web comic Homestuck take place in the year 2422, on April 13th.