GNG2

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Guanine nucleotide binding protein (G protein), gamma 2
Protein GNG2 PDB 1gg2.png
PDB rendering based on 1gg2.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbol GNG2
External IDs OMIM606981 MGI102705 HomoloGene40715 GeneCards: GNG2 Gene
Orthologs
Species Human Mouse
Entrez 54331 14702
Ensembl ENSG00000186469 ENSMUSG00000043004
UniProt P59768 P63213
RefSeq (mRNA) NM_001243773 NM_001038637
RefSeq (protein) NP_001230702 NP_001033726
Location (UCSC) Chr 14:
52.29 – 52.45 Mb
Chr 14:
19.87 – 19.98 Mb
PubMed search [1] [2]

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.[1][2]

Heterotrimeric G proteins play vital roles in cellular responses to external signals. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.[supplied by OMIM][2]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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NicotineDopaminergic_WP1602 go to article go to article go to article Go to article go to article Go to article Go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article Go to article go to article go to article go to article go to article Go to article Go to article go to article Go to article Go to article Go to article go to article Go to article Go to article Go to article go to article go to article go to article go to article go to article go to article Go to article go to article Go to article Go to article go to article go to article Go to article go to article Go to article Go to article go to article
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Nicotine Activity on Dopaminergic Neurons edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". 

References[edit]

  1. ^ Modarressi MH, Taylor KE, Wolfe J (Jul 2000). "Cloning, characterization, and mapping of the gene encoding the human G protein gamma 2 subunit". Biochem Biophys Res Commun 272 (2): 610–5. doi:10.1006/bbrc.2000.2832. PMID 10833460. 
  2. ^ a b "Entrez Gene: GNG2 guanine nucleotide binding protein (G protein), gamma 2". 

Further reading[edit]