Dual-specificity kinase

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Dual-specificity kinase
Identifiers
EC number 2.7.12.1
CAS number 134549-83-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In biochemistry, a dual-specificity kinase (EC 2.7.12.1) is a kinase that can act as both tyrosine kinase and serine/threonine kinase.

MEKs, involved in MAP pathways, are principal examples of dual-specificity kinases. Other common examples include:

The systematic name of this enzyme class is ATP:protein phosphotransferase (Ser/Thr- and Tyr-phosphorylating).

References[edit]