PRKCSH

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Protein kinase C substrate 80K-H
Identifiers
Symbols PRKCSH ; AGE-R2; G19P1; PCLD; PKCSH; PLD1
External IDs OMIM177060 MGI107877 HomoloGene2056 ChEMBL: 5242 GeneCards: PRKCSH Gene
EC number 2.7.11.1
RNA expression pattern
PBB GE PRKCSH 200707 at tn.png
PBB GE PRKCSH 214080 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5589 19089
Ensembl ENSG00000130175 ENSMUSG00000003402
UniProt P14314 O08795
RefSeq (mRNA) NM_001001329 NM_008925
RefSeq (protein) NP_001001329 NP_032951
Location (UCSC) Chr 19:
11.55 – 11.56 Mb
Chr 9:
22 – 22.01 Mb
PubMed search [1] [2]

Glucosidase 2 subunit beta is an enzyme that in humans is encoded by the PRKCSH gene.[1]

This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed.[1]

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