3-Phosphoglyceric acid

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3-Phosphoglyceric acid
Skeletal formula
Ball-and-stick model
Names
IUPAC name
(2R)-2-Hydroxy-3-phosphonooxypropanoic acid
Identifiers
820-11-1 N
ChEBI CHEBI:17794 YesY
ChEMBL ChEMBL1160563 YesY
ChemSpider 388326 YesY
Jmol-3D images Image
PubChem 439183
Properties
C3H7O7P
Molar mass 186.06 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

3-Phosphoglyceric acid (3PG), or glycerate 3-phosphate (GP), is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle.[citation needed] This chemical is often termed PGA when referring to the Calvin cycle. In the Calvin cycle, 3-Phosphoglycerate is the product of the spontaneous split of an unstable 6-carbon intermediate formed by CO2 fixation. Thus, two 3-phosphoglycerate molecules are produced for each molecule of CO2 fixed.

Glycolysis[edit]

1,3-bisphospho-D-glycerate 3-phosphoglycerate kinase 3-phospho-D-glycerate Phosphoglyceromutase 2-phospho-D-glycerate
1,3-bisphospho-D-glycerate.svg   3-phospho-D-glycerate.svg   2-phospho-D-glycerate wpmp.png
ADP ATP
Biochem reaction arrow reversible YYYY horiz med.png Biochem reaction arrow reversible NNNN horiz med.png
ADP ATP
   
  3-phosphoglycerate kinase   Phosphoglyceromutase

Compound C00236 at KEGG Pathway Database. Enzyme 2.7.2.3 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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GlycolysisGluconeogenesis_WP534 go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to Entrez go to article go to article go to article go to article go to article go to WikiPathways go to article go to Entrez go to article
|{{{bSize}}}px|alt=Glycolysis and Gluconeogenesis edit|]]
Glycolysis and Gluconeogenesis edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534". 

Calvin cycle[edit]

In the light-independent reactions (also known as the Calvin cycle), two 3-phosphoglycerate molecules are synthesized, one of which continues through the Calvin cycle to be regenerated to Rubisco and the other is reduced to form one molecule of glyceraldehyde 3-phosphate (G3P). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule that is easily reduced.

Amino acid synthesis[edit]

Glycerate 3-phosphate is also a precursor for serine, which, in turn, can create cysteine and glycine through the homocysteine cycle.

See also[edit]

Notes[edit]