Z-drug: Difference between revisions
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[[Image:Zolpidem_structure.svg|thumb|right|200px|Chemical structure of the prototypical Z-drug [[zolpidem]].]] |
[[Image:Zolpidem_structure.svg|thumb|right|200px|Chemical structure of the prototypical Z-drug [[zolpidem]].]] |
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'''Z-drugs''' are a group of [[nonbenzodiazepine]] drugs with effects similar to [[benzodiazepines]] which are used in the treatment of [[insomnia]].<ref>{{cite journal |author= |title=What's wrong with prescribing hypnotics? |journal=Drug Ther Bull |volume=42 |issue=12 |pages=89–93 |year=2004 |month=December |pmid=15587763 |doi= |url=http://dtb.bmj.com/cgi/content/full/42/12/89}}</ref> Some Z drugs may have advantages over benzodiazepines. Benzodiazepines actually worsen [[sleep architecture]] whereas certain Z drugs such as [[zaleplon]] have less or no disruption of sleep architecture.<ref>{{cite journal |author=Barbera J, Shapiro C |title=Benefit-risk assessment of zaleplon in the treatment of insomnia |journal=Drug Saf |volume=28 |issue=4 |pages=301–18 |year=2005 |pmid=15783240 |doi= |url=}}</ref> |
'''Z-drugs''' are a group of [[nonbenzodiazepine]] drugs with effects similar to [[benzodiazepines]] which are used in the treatment of [[insomnia]].<ref>{{cite journal |author= |title=What's wrong with prescribing hypnotics? |journal=Drug Ther Bull |volume=42 |issue=12 |pages=89–93 |year=2004 |month=December |pmid=15587763 |doi= |url=http://dtb.bmj.com/cgi/content/full/42/12/89}}</ref> They are called such because their names tend to start with the letter "Z". Some Z drugs may have advantages over benzodiazepines. Benzodiazepines actually worsen [[sleep architecture]] whereas certain Z drugs such as [[zaleplon]] have less or no disruption of sleep architecture.<ref>{{cite journal |author=Barbera J, Shapiro C |title=Benefit-risk assessment of zaleplon in the treatment of insomnia |journal=Drug Saf |volume=28 |issue=4 |pages=301–18 |year=2005 |pmid=15783240 |doi= |url=}}</ref> |
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== List of Z-drugs == |
== List of Z-drugs == |
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Revision as of 14:41, 8 June 2010
Z-drugs are a group of nonbenzodiazepine drugs with effects similar to benzodiazepines which are used in the treatment of insomnia.[1] They are called such because their names tend to start with the letter "Z". Some Z drugs may have advantages over benzodiazepines. Benzodiazepines actually worsen sleep architecture whereas certain Z drugs such as zaleplon have less or no disruption of sleep architecture.[2]
List of Z-drugs
- Zaleplon (Sonata)
- Zolpidem (Ambien)
- Zopiclone (Imovane)
- Eszopiclone (Lunesta)
See also
References
- ^ "What's wrong with prescribing hypnotics?". Drug Ther Bull. 42 (12): 89–93. 2004. PMID 15587763.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Barbera J, Shapiro C (2005). "Benefit-risk assessment of zaleplon in the treatment of insomnia". Drug Saf. 28 (4): 301–18. PMID 15783240.