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Trional structure.png
Trional ball-and-stick.png
Clinical data
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ECHA InfoCard100.000.858 Edit this at Wikidata
Chemical and physical data
Molar mass242.356 g/mol g·mol−1
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Trional (Methylsulfonal) is a sedative-hypnotic[1] and anesthetic drug with GABAergic actions[citation needed]. It has similar effects to sulfonal, except it is faster acting.[2]


Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888.[3]

Appeared in Agatha Christie's "Murder on the Orient Express", "And Then There Were None" and other novels as a sleep inducing sedative, and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as a hypnotic. Sax Rohmer also references trional in his novel Dope.

See also[edit]


  1. ^ (1907). Merck's 1907 Index. N. Y.: Merck & Co., p. 448.
  2. ^ Sajous, Charles E. (1896). Annual of the Universal Medical Sciences
    Philadelphia: F. A. Davis, v. 5, p. A-156.
  3. ^ Drinkwater, H. (1924). Fifty years of medical progress, 1873-1922.
    New York: The Macmillan Company, p. 40.