SL-164

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SL-164
SL-164.svg
Clinical data
ATC code
  • none
Identifiers
  • 5-chloro-3-(4-chloro-2-methylphenyl)-2-methylquinazolin-4-one
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H12Cl2N2O
Molar mass319.185 g·mol−1
3D model (JSmol)
  • ClC1=CC(C)=C(N2C(C)=NC3=CC=CC(Cl)=C3C2=O)C=C1
  • InChI=1S/C16H12Cl2N2O/c1-9-8-11(17)6-7-14(9)20-10(2)19-13-5-3-4-12(18)15(13)16(20)21/h3-8H,1-2H3
  • Key:KUIHLOHNUGOCTO-UHFFFAOYSA-N

SL-164 is an analogue of methaqualone developed in the late 1960s by a team at Sumitomo.[1] SL-164 has similar sedative, hypnotic and anticonvulsant properties to the parent compound, but was never marketed for clinical use.[2]

References[edit]

  1. ^ US 3651230, "Compositions And Methods For Tranquilizing With Substituted 3-Phenyl-4-Quinazolinone Derivatives" 
  2. ^ Saito C, Sakai S, Yukawa Y, Yamamoto H, Takagi H (December 1969). "Pharmacological studies on 2-methyl-3(2'-methyl-4'-chlorophenyl)-5-chloro-4[H)-quinazolinone (SL-164)". Arzneimittel-Forschung. 19 (12): 1945–9. PMID 4985336.