CDH6

CDH6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LND
Identifiers
Aliases	CDH6, CAD6, KCAD, cadherin 6
External IDs	OMIM: 603007; MGI: 107435; HomoloGene: 21027; GeneCards: CDH6; OMA:CDH6 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	31,329,146 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	13,173,761 bp
RNA expression pattern
	Top expressed in
	beta cell; ; kidney tubule; ; tibial arteries; ; human kidney; ; endothelial cell; ; vena cava; ; gallbladder; ; sural nerve; ; lateral nuclear group of thalamus; ; metanephric glomerulus;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; hair follicle; ; ascending aorta; ; aortic valve; ; Rostral migratory stream; ; renal corpuscle; ; efferent ductule; ; ciliary body; ; iris;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; metal ion binding; cytoskeletal protein binding; protein homodimerization activity; cadherin binding;
Cellular component	integral component of membrane; plasma membrane; membrane; cell surface; catenin complex;
Biological process	Notch signaling pathway; cell adhesion; adherens junction organization; homophilic cell adhesion via plasma membrane adhesion molecules; cell-cell junction assembly; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; cell-cell adhesion; cell morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	1004
	12563
	ENSG00000113361
	ENSMUSG00000039385
	P55285
	P97326
	NM_004932; NM_001362435
	NM_007666
	NP_004923; NP_001349364
	NP_031692
	Wikidata
View/Edit Human	View/Edit Mouse

Cadherin-6 is a protein that in humans is encoded by the CDH6 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113361 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039385 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shimoyama Y, Gotoh M, Terasaki T, Kitajima M, Hirohashi S (June 1995). "Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells". Cancer Res. 55 (10): 2206–11. PMID 7743525.
^ Chalmers IJ, Hofler H, Atkinson MJ (June 1999). "Mapping of a cadherin gene cluster to a region of chromosome 5 subject to frequent allelic loss in carcinoma". Genomics. 57 (1): 160–3. doi:10.1006/geno.1998.5717. PMID 10191097.
^ "Entrez Gene: CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)".

External links

CDH6 human gene location in the UCSC Genome Browser.
CDH6 human gene details in the UCSC Genome Browser.

Template:PBB Controls

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113361 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000039385 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7743525-5] Shimoyama Y, Gotoh M, Terasaki T, Kitajima M, Hirohashi S (June 1995). "Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells". Cancer Res. 55 (10): 2206–11. PMID 7743525.

[pmid10191097-6] Chalmers IJ, Hofler H, Atkinson MJ (June 1999). "Mapping of a cadherin gene cluster to a region of chromosome 5 subject to frequent allelic loss in carcinoma". Genomics. 57 (1): 160–3. doi:10.1006/geno.1998.5717. PMID 10191097.

[entrez-7] "Entrez Gene: CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)".

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References

Further reading

External links