Dexibuprofen

Dexibuprofen
Clinical data
Trade names	Seractil, Deltaran, Ibusoft, Monactil
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	M01AE14 (WHO) ;
Identifiers
	IUPAC name (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid;
CAS Number	51146-56-6 ;
PubChem CID	39912;
ChemSpider	36498 ;
UNII	671DKG7P5S;
KEGG	D03715 ;
ChEBI	CHEBI:43415 ;
ChEMBL	ChEMBL175 ;
CompTox Dashboard (EPA)	DTXSID9048724 ;
ECHA InfoCard	100.106.960
Chemical and physical data
Formula	C13H18O2
Molar mass	206.285 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H](c1ccc(cc1)CC(C)C)C(=O)O;
	InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1 ; Key:HEFNNWSXXWATRW-JTQLQIEISA-N ;
	(verify)

Dexibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

It is the active dextrorotatory enantiomer of ibuprofen.^[1] Most ibuprofen formulations contain a racemic mixture of both isomers.

References

^ Hardikar MS (2008). "Chiral non-steroidal anti-inflammatory drugs—a review". J Indian Med Assoc. 106 (9): 615–8, 622, 624. PMID 19552094.

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[pmid19552094-1] Hardikar MS (2008). "Chiral non-steroidal anti-inflammatory drugs—a review". J Indian Med Assoc. 106 (9): 615–8, 622, 624. PMID 19552094.

[1]

v t e Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones / pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Difenamizole Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡
salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate
acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bufexamac Bumadizone Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indometacin Indometacin farnesil Isoxepac Ketorolac Lonazolac Mofezolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†
oxicams	Ampiroxicam Droxicam Isoxicam Lornoxicam Meloxicam Piroxicam Pivoxicam Tenoxicam
propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pelubiprofen Piketoprofen Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ Zaltoprofen COX-inhibiting nitric oxide donator: Naproxcinod
n-arylanthranilic acids (fenamates)	Azapropazone Clonixin Etofenamate Floctafenine Flufenamic acid Flunixin Flutiazin Glafenine^† Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid
COX-2 inhibitors (coxibs)	Apricoxib Celecoxib (+tramadol) Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†
other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase / orgotein Tenidap
NSAID combinations	Ibuprofen/famotidine Ibuprofen/hydrocodone Ibuprofen/oxycodone Ibuprofen/paracetamol Meloxicam/bupivacaine Naproxen/diphenhydramine Naproxen/esomeprazole
Key: underline indicates initially developed first-in-class compound of specific group; ^#WHO-Essential Medicines; ^†withdrawn drugs; ^‡veterinary use.
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