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In September 2005, Griffin covered the aftermath of Hurricane Katrina. Griffin's reports about the looting by some New Orleans police officers led to a police investigation. He also broke stories about nursing home deaths after Katrina.
Griffin won a business and financial reporting Emmy Awards in 2005 for his reports on a fault in Ford Motor Company vehicles which caused them to catch fire. He earned his second Emmy in 2006 for the CNN Presents documentary How to Rob a Bank and a third in 2007 for "Hidden Spending", an Anderson Cooper 360° segment about congressional spending. He earned a Peabody award in 2015 for “Crisis at the VA”, a story that broke the scandals of hidden wait times and deaths at VA hospitals across the country. His fourth Emmy, in 2017, was awarded for “Trump University Fraud”, about fraudulent practices behind Donald Trump's real estate school.
- "Anchors Reporters Griffin Drew". CNN. Retrieved 2008-05-05.