mir-395 microRNA precursor family

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mir-395 microRNA precursor family
Symbol mir-395
Rfam RF00451
miRBase MI0001007
miRBase family MIPF0000016
Other data
RNA type Gene; miRNA
Domain(s) Eukaryota
GO 0035195 0035068
SO 0001244
PDB structures PDBe

mir-395 is a non-coding RNA called a microRNA that was identified in both Arabidopsis thaliana and Oryza sativa computationally and was later experimentally verified. mir-395 is thought to target mRNAs coding for ATP sulphurylases.[1] The mature sequence is excised from the 3' arm of the hairpin.

miR-395 is upregulated in Arabidopsis during sulphate-limited conditions, when the mature miRNA then regulates sulphur transporters and ATP sulphurylases.[2][3]


  1. ^ Jones-Rhoades, MW; Bartel DP (2004). "Computational Identification of Plant MicroRNAs and Their Targets, Including a Stress-Induced miRNA". Mol Cell. 14 (6): 787–799. doi:10.1016/j.molcel.2004.05.027. PMID 15200956. 
  2. ^ Liang, G; Yang, F; Yu, D (Jun 1, 2010). "MicroRNA395 mediates regulation of sulfate accumulation and allocation in Arabidopsis thaliana". The Plant journal : for cell and molecular biology. 62 (6): 1046–57. doi:10.1111/j.1365-313X.2010.04216.x. PMID 20374528. 
  3. ^ Liang, G; Yu, D (October 2010). "Reciprocal regulation among miR395, APS and SULTR2;1 in Arabidopsis thaliana". Plant signaling & behavior. 5 (10): 1257–9. doi:10.4161/psb.5.10.12608. PMC 3115361Freely accessible. PMID 20935495. 

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