Picotamide

Picotamide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B01AC03 (WHO) ;
Identifiers
	IUPAC name 4-methoxy-N,N'-bis(pyridin-3-ylmethyl)isophthalamide;
PubChem CID	4814;
ChemSpider	4649 ;
UNII	654G2VCI4Q;
CompTox Dashboard (EPA)	DTXSID40186498 ;
ECHA InfoCard	100.046.572
Chemical and physical data
Formula	C21H20N4O3
Molar mass	376.409 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(NCc1cccnc1)c3cc(C(=O)NCc2cccnc2)c(OC)cc3;
	InChI InChI=1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27) ; Key:KYWCWBXGRWWINE-UHFFFAOYSA-N ;
	(verify)

Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor.^[1]

References

^ Ratti, S; Quarato, P; Casagrande, C; Fumagalli, R; Corsini, A (1998). "Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes". European Journal of Pharmacology. 355 (1): 77–83. doi:10.1016/S0014-2999(98)00467-1. PMID 9754941.

This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it.