SYT6

SYT6
Identifiers
Aliases	SYT6, sytVI, synaptotagmin 6
External IDs	OMIM: 607718; MGI: 1859544; HomoloGene: 10301; GeneCards: SYT6; OMA:SYT6 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	114,153,880 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	103,552,885 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; ganglionic eminence; ; nucleus accumbens; ; hypothalamus; ; tibialis anterior muscle; ; caudate nucleus; ; primary visual cortex; ; putamen; ; mucosa of ileum; ; prefrontal cortex;
	Top expressed in
	multiform layer of neocortex; ; superior frontal gyrus; ; olfactory bulb; ; pretectal area; ; Rostral migratory stream; ; primary visual cortex; ; lumbar spinal ganglion; ; olfactory tubercle; ; dentate gyrus of hippocampal formation granule cell; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; protein homodimerization activity; clathrin binding; calcium-dependent protein binding; metal ion binding; protein binding; identical protein binding; calcium-dependent phospholipid binding; syntaxin binding; phosphatidylserine binding; SNARE binding;
Cellular component	cytoplasm; integral component of membrane; cytosol; membrane; perinuclear endoplasmic reticulum; synapse; synaptic vesicle membrane; cell junction; cytoplasmic vesicle; plasma membrane; extrinsic component of membrane; glutamatergic synapse; integral component of synaptic membrane; exocytic vesicle;
Biological process	acrosomal vesicle exocytosis; acrosome reaction; regulation of calcium ion-dependent exocytosis; calcium ion-regulated exocytosis of neurotransmitter; vesicle fusion; presynaptic dense core vesicle exocytosis; regulation of dopamine secretion; synaptic vesicle exocytosis; vesicle-mediated transport; calcium-ion regulated exocytosis; cellular response to calcium ion;
	Sources:Amigo / QuickGO
Orthologs
	148281
	54524
	ENSG00000134207
	ENSMUSG00000027849
	Q5T7P8
	Q9R0N8
NM_001253772; NM_001270805; NM_205848; NM_001366223; NM_001366224;
	NM_001366225; NM_001366226
NM_001276676; NM_001276677; NM_001276679; NM_001276680; NM_001276681;
	NM_018800
NP_001257734; NP_995320; NP_001240701; NP_001353152; NP_001353153;
	NP_001353154; NP_001353155
NP_001263605; NP_001263606; NP_001263608; NP_001263609; NP_001263610;
	NP_061270
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptotagmin-6 is a protein that in humans is encoded by the SYT6 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000134207 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027849 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Craxton M (Sep 2001). "Genomic analysis of synaptotagmin genes". Genomics. 77 (1–2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631.
^ "Entrez Gene: SYT6 synaptotagmin VI".

References

Further reading