Progress M1-8 was launched by a Soyuz-U carrier rocket from Site 1/5 at the Baikonur Cosmodrome. Launch occurred at 20:13:39 GMT on 21 March 2002. The spacecraft docked with the Aft port of the Zvezda module at 20:57:56 GMT on 24 March. It remained docked for three months before undocking at 08:26:30 GMT on 25 June to make way for Progress M-46. It was deorbited at 11:35:00 GMT on the same day. The spacecraft burned up in the atmosphere over the Pacific Ocean, with any remaining debris landing in the ocean at around 12:26:52 GMT.
Progress M1-8 carried supplies to the International Space Station, including food, water and oxygen for the crew and equipment for conducting scientific research.
Payloads are separated by bullets ( · ), launches by pipes ( | ). Manned flights are indicated in bold text. Uncatalogued launch failures are listed in italics. Payloads deployed from other spacecraft are denoted in brackets.