ATP2B3

ATP2B3
Identifiers
Aliases	ATP2B3, CFAP39, CLA2, OPCA, PMCA3, PMCA3a, SCAX1, ATPase plasma membrane Ca2+ transporting 3
External IDs	OMIM: 300014; MGI: 1347353; HomoloGene: 123775; GeneCards: ATP2B3; OMA:ATP2B3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	153,582,939 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	72,614,611 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; middle temporal gyrus; ; primary visual cortex; ; right hemisphere of cerebellum; ; frontal pole; ; superior frontal gyrus; ; cerebellar vermis; ; postcentral gyrus; ; paraflocculus of cerebellum;
	Top expressed in
	cerebellar cortex; ; dentate gyrus of hippocampal formation granule cell; ; hippocampus proper; ; primary visual cortex; ; superior frontal gyrus; ; hypothalamus; ; adrenal gland; ; basal forebrain; ; striatum of neuraxis; ; secondary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; nucleotide binding; hydrolase activity; PDZ domain binding; calmodulin binding; ATP binding; P-type calcium transporter activity; protein binding; calcium ion transmembrane transporter activity; P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration;
Cellular component	extracellular vesicle; integral component of membrane; Golgi apparatus; intracellular membrane-bounded organelle; integral component of plasma membrane; membrane; plasma membrane; presynapse; glutamatergic synapse; GABA-ergic synapse;
Biological process	calcium ion transport; regulation of cardiac conduction; cellular calcium ion homeostasis; ion transport; calcium ion transmembrane transport; ion transmembrane transport; transport; regulation of cytosolic calcium ion concentration; regulation of presynaptic cytosolic calcium ion concentration; calcium ion export across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	492
	320707
	ENSG00000067842
	ENSMUSG00000031376
	Q16720
	n/a
	NM_001001344; NM_021949; NM_001388360; NM_001388361; NM_001388362
	NM_177236; NM_001310537
	NP_001001344; NP_068768
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Plasma membrane calcium-transporting ATPase 3 is an enzyme that in humans is encoded by the ATP2B3 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000067842 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031376 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang MG, Yi H, Hilfiker H, Carafoli E, Strehler EE, McBride OW (Jun 1994). "Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26→p25 and Xq28, respectively". Cytogenet Cell Genet. 67 (1): 41–5. doi:10.1159/000133794. PMID 8187550.
^ "Entrez Gene: ATP2B3 ATPase, Ca++ transporting, plasma membrane 3".

References

Further reading