GNB2

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GNB2
Protein GNB2 PDB 1b9x.png
Identifiers
AliasesGNB2, G protein subunit beta 2
External IDsMGI: 95784 HomoloGene: 68451 GeneCards: GNB2
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for GNB2
Genomic location for GNB2
Band7q22.1Start100,673,531 bp[1]
End100,679,174 bp[1]
RNA expression pattern
PBB GE GNB2 200852 x at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005273

NM_010312

RefSeq (protein)

NP_005264

NP_034442

Location (UCSC)Chr 7: 100.67 – 100.68 MbChr 5: 137.53 – 137.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 is a protein that in humans is encoded by the GNB2 gene.[5][6]

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.[6]

References[edit]

Further reading[edit]