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Guanine nucleotide binding protein (G protein), gamma 3
Symbol GNG3
External IDs OMIM608941 MGI102704 HomoloGene22575 GeneCards: GNG3 Gene
RNA expression pattern
PBB GE GNG3 222005 s at tn.png
More reference expression data
Species Human Mouse
Entrez 2785 14704
Ensembl ENSG00000162188 ENSMUSG00000071658
UniProt P63215 P63216
RefSeq (mRNA) NM_012202 NM_010316
RefSeq (protein) NP_036334 NP_034446
Location (UCSC) Chr 11:
62.71 – 62.71 Mb
Chr 19:
8.84 – 8.84 Mb
PubMed search [1] [2]

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 is a protein that in humans is encoded by the GNG3 gene.[1][2]

G proteins are heterotrimers of alpha, beta, and gamma subunits. Gamma subunits, such as GNG3, contribute to the specificity of the hundreds of receptor signaling pathways involving G proteins (Schwindinger et al., 2004).[supplied by OMIM][2]


  1. ^ Downes GB, Gautam N (Mar 2000). "The G protein subunit gene families". Genomics 62 (3): 544–52. doi:10.1006/geno.1999.5992. PMID 10644457. 
  2. ^ a b "Entrez Gene: GNG3 guanine nucleotide binding protein (G protein), gamma 3". 

Further reading[edit]