On 1 February 1961, the route was extended from Farringdon Street to Hampstead Heath via Grays Inn Road and King's Cross replacing trolleybus route 513. On 8 January 1972, it was withdrawn between King's Cross and Hampstead and replaced by route 46. On 28 October 1978, the route was extended from King's Cross to Archway station.
On 3 August 1985, route 45 was converted to one man operation with the AEC Routemasters replaced by Leyland Titans. On 10 November 1990, it was withdrawn between South Kensington and Brixton, with the southern terminus becoming Lambeth Town Hall, while at the northern end it was withdrawn between King's Cross and Archway.
The southern terminus changed again to Brixton garage on 29 January 1994, and Streatham Hill on 14 November 1998.
Upon being re-tendered, route 45 was retained by London Central with a new contract commencing on 13 November 2010.[1]
Media related to London Buses route 45 at Wikimedia Commons
