mir-46/mir-47/mir-281 microRNA precursor family
| mir-46/mir-47/mir-281 microRNA precursor family | |
|---|---|
 Predicted secondary structure and sequence conservation of mir-46 | |
| Identifiers | |
| Symbol | mir-46 |
| Rfam | RF00249 |
| miRBase | MI0000017 |
| miRBase family | MIPF0000087 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain(s) | Eukaryota |
| GO | GO:0035195 GO:0035068 |
| SO | SO:0001244 |
| PDB structures | PDBe |
In molecular biology, mir-46 (MI0000017) and mir-47 (MI0000018) are microRNA expressed in C. elegans from related hairpin precursor sequences.[1] The predicted hairpin precursor sequences for Drosophila mir-281 (MI0000366, MI0000370)[2][3] are also related and, hence, belong to this family. The hairpin precursors (represented here) are predicted based on base pairing and cross-species conservation; their extents are not known. In this case, the mature sequences are expressed from the 3' arms of the hairpin precursors.
References
- ^ Lau, NC; Lim LP; Weinstein EG; Bartel DP (2001). "An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans". Science. 294 (5543): 858–862. doi:10.1126/science.1065062. PMID 11679671.
- ^ Lai, EC; Tomancak P; Williams RW; Rubin GM (2003). "Computational identification of Drosophila microRNA genes". Genome Biol. 4 (7): R42–. doi:10.1186/gb-2003-4-7-r42. PMC 193629. PMID 12844358.
{{cite journal}}: CS1 maint: extra punctuation (link) CS1 maint: unflagged free DOI (link) - ^ Aravin, AA; Lagos-Quintana M; Yalcin A; Zavolan M; Marks D; Snyder B; Gaasterland T; Meyer J; Tuschl T (2003). "The small RNA profile during Drosophila melanogaster development". Dev Cell. 5 (2): 337–350. doi:10.1016/S1534-5807(03)00228-4. PMID 12919683.
External links
- Page for mir-46/mir-47/mir-281 microRNA precursor family at Rfam
- MI0000017
- MI0000018
- MI0000366
- MI0000370
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