The city has grown over the centuries on both banks and is now a metropolitan area that spreads out from the Musi river. Hyderabad was founded as Bhagyanagar on the banks of Musi river by Muhammad Quli Qutb Shah, Sultan of the Qutb Shahi dynasty, in 1590; this relocation was intended to relieve a water shortage the dynasty had experienced at their old headquarters at Golkonda.
Secunderabadpronunciation (help·info) (Telugu: సికింద్రాబాద్) is the twin city of Hyderabad and the two cities are popularly called Twin cities. In common parlance however, Secunderabad is seldom used these days outside the twin cities. The city of Secunderabad which was once said to be modern compared to its twin during the Nizam rule, has grown tremendously over the years to catch up with the metropolis of Hyderabad. The cities present different fusion of cultures with Secunderabad having developed under direct British rule until 1948, and the city of Hyderabad, as the capital of a princely state. It was founded in the 18th century as a cantonment, and has a large army and Air force presence to this date. Today, the Secunderabad Cantonment is the largest among the 62 cantonments in India. Named after Sikandar Jah, the third Nizam of the Asaf Jahi dynasty, till recently Secunderabad had its own municipality and city government. Sir Ronald Ross conducted his initial research on the cause of malaria in the city of Secunderabad. Secunderabad Railway Station is the largest station serving the city and also the headquarters of South Central Railway zone of the Indian Railways.
As the historical region of Hyderabad, the old city contains many landmark buildings including, Charminar (literally "Four minarets"), a structure built on the spot where Quli Qutb Shah prayed for the end to a plague epidemic.
Yeduguri Sandinti Rajasekhara Reddy (8 July 1949 – 2 September 2009), popularly known as YSR, is the former Chief Minister of the Indian state of Andhra Pradesh. He was born at Jammalamadugu Mission Hospital near Pulivendula to Y. S. Raja Reddy and Jayamma. He graduated with a degree in medical science from Mahadevappa Rampure Medical College (MRMC), Gulbarga University, Karnataka and completed his House Surgeonship at S.V. Medical College, Tirupati, Andhra Pradesh. He was the elected leader of the House Surgeon's Association at S.V. Medical College, Tirupati. From 1980 to 1983 he was a minister holding important portfolios related to Rural Development, Medical Health and Education. He was elected to the Lok Sabha from Kadapa constituency four times and was elected to the Andhra Pradesh State Assembly six times from Pulivendula constituency. Reddy was the leader of the opposition in the Andhra Pradesh State Assembly for five years. During mid-summer of 2003, he led a 1400 km long paadayaatra (journey by foot), covering some of the backward areas in the state to understand the ground realities and living conditions of the people there. He was elected as the Chief Minister of Andhra Pradesh by the Legislature party of the Indian National Congress in the May 2004 elections and remained as Chief minister until hi tragic death of helicopter crash in September 2009.