Jump to content

5'-acylphosphoadenosine hydrolase

From Wikipedia, the free encyclopedia
5'-acylphosphoadenosine hydrolase
Identifiers
EC no.3.6.1.20
CAS no.37289-31-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a 5'-acylphosphoadenosine hydrolase (EC 3.6.1.20) is an enzyme that catalyzes the chemical reaction

5'-acylphosphoadenosine + H2O AMP + a carboxylate

Thus, the two substrates of this enzyme are 5'-acylphosphoadenosine and H2O, whereas its two products are AMP and carboxylate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is 5'-acylphosphoadenosine acylhydrolase. This enzyme is also called 5-phosphoadenosine hydrolase. This enzyme participates in purine metabolism.

References

[edit]
  • Kellerman GM (May 1959). "Isolation and characteristics of the enzyme acyl 5'-nucleotidase". Biochimica et Biophysica Acta. 33 (1): 101–5. doi:10.1016/0006-3002(59)90502-5. PMID 13651188.