Ag+-exporting ATPase

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silver-exporting ATPase
Identifiers
EC number 3.6.3.53
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an Ag+-exporting ATPase (EC 3.6.3.53) is an enzyme that catalyzes the chemical reaction

ATP + H2O + Ag+in ADP + phosphate + Ag+out

The 3 substrates of this enzyme are ATP, H2O, and Ag+, whereas its 3 products are ADP, phosphate, and Ag+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Ag+-exporting).

References[edit]

  • Gupta A, Matsui K, Lo JF, Silver S (1999). "Molecular basis for resistance to silver cations in Salmonella". Nat. Med. 5 (2): 183–188. PMID 9930866. doi:10.1038/5545. 
  • Bury NR, Grosell M, Grover AK, Wood CM (1999). "ATP-dependent silver transport across the basolateral membrane of rainbow trout gills". Toxicol. Appl. Pharmacol. 159 (1): 1–8. PMID 10448119. doi:10.1006/taap.1999.8706.