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Heme-transporting ATPase

From Wikipedia, the free encyclopedia
heme-transporting ATPase
Identifiers
EC no.3.6.3.41
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a heme-transporting ATPase (EC 3.6.3.41) is an enzyme that catalyzes the chemical reaction

ATP + H2O + hemein ADP + phosphate + hemeout

The 3 substrates of this enzyme are ATP, H2O, and heme, whereas its 3 products are ADP, phosphate, and heme.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (heme-exporting). This enzyme participates in abc transporters - general.

References

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  • Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. Advances in Microbial Physiology. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 978-0-12-027740-7. PMID 9889977.
  • Jekabsons W, Schuster W (1995). "orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria". Mol. Gen. Genet. 246 (2): 166–73. doi:10.1007/BF00294679. PMID 7862087.
  • Ramseier TM, Winteler HV, Hennecke H (1991). "Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes". J. Biol. Chem. 266 (12): 7793–803. PMID 1850420.