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RHOB

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RHOB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRHOB, ARH6, ARHB, MST081, MSTP081, RHOH6, ras homolog family member B
External IDsOMIM: 165370; MGI: 107949; HomoloGene: 68377; GeneCards: RHOB; OMA:RHOB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004040

NM_007483

RefSeq (protein)

NP_004031

NP_031509

Location (UCSC)Chr 2: 20.45 – 20.45 MbChr 12: 8.55 – 8.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.[5][6]

RHOB is a member of the Rho GTP-binding protein family.[7]

Interactions

RHOB has been shown to interact with CIT,[8] ARHGEF3,[9] ARHGDIG[10] and RHPN2.[11]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143878Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054364Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RHOB ras homolog gene family, member B".
  6. ^ Chardin P, Madaule P, Tavitian A (March 1988). "Coding sequence of human rho cDNAs clone 6 and clone 9". Nucleic Acids Research. 16 (6): 2717. doi:10.1093/nar/16.6.2717. PMC 336400. PMID 3283705.
  7. ^ Wennerberg K, Der CJ (March 2004). "Rho-family GTPases: it's not only Rac and Rho (and I like it)". Journal of Cell Science. 117 (Pt 8): 1301–12. doi:10.1242/jcs.01118. PMID 15020670.
  8. ^ Madaule, P; Furuyashiki T; Reid T; Ishizaki T; Watanabe G; Morii N; Narumiya S (Dec 1995). "A novel partner for the GTP-bound forms of rho and rac". FEBS Lett. 377 (2). NETHERLANDS: 243–8. doi:10.1016/0014-5793(95)01351-2. ISSN 0014-5793. PMID 8543060. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
  9. ^ Arthur, William T; Ellerbroek Shawn M; Der Channing J; Burridge Keith; Wennerberg Krister (Nov 2002). "XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC". J. Biol. Chem. 277 (45). United States: 42964–72. doi:10.1074/jbc.M207401200. ISSN 0021-9258. PMID 12221096. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)
  10. ^ Zalcman, G; Closson V; Camonis J; Honoré N; Rousseau-Merck M F; Tavitian A; Olofsson B (Nov 1996). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48). UNITED STATES: 30366–74. doi:10.1074/jbc.271.48.30366. ISSN 0021-9258. PMID 8939998. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)
  11. ^ Mircescu, Hortensia; Steuve Séverine; Savonet Valérie; Degraef Chantal; Mellor Harry; Dumont Jacques E; Maenhaut Carine; Pirson Isabelle (Dec 2002). "Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP". Eur. J. Biochem. 269 (24). Germany: 6241–9. doi:10.1046/j.1432-1033.2002.03343.x. ISSN 0014-2956. PMID 12473120. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Further reading

See also

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