Small nucleolar RNA SNORA11
|Small nucleolar RNA SNORA11|
|RNA type||Gene; snRNA; snoRNA; H/ACA-box|
Small nucleolar RNA SNORA11 (also known as U107) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).
U107 has a predicted hairpin-hinge-hairpin-tail structure and is predicted to be a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by RT-PCR from blood cells and its expression confirmed by Northern blot analysis. There is no predicted RNA target for this guide snRNA.
- Kiss, Arnold M.; Jády, Beáta E.; Bertrand, Edouard; Kiss, Tamás (2004). "Human Box H/ACA Pseudouridylation Guide RNA Machinery". Molecular and Cellular Biology. 24 (13): 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC . PMID 15199136.
- Gu, Ai-Di; Zhou, Hui; Yu, Chun-Hong; Qu, Liang-Hu (2005). "A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes". Nucleic Acids Research. 33 (22): e194. doi:10.1093/nar/gni185. PMC . PMID 16361266.
- Lestrade, Laurent; Weber, Michel J. (2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Supplement 1: Database Issue): D158–D162. CiteSeerX . doi:10.1093/nar/gkj002. PMC . PMID 16381836.
- Page for Small nucleolar RNA SNORA11 at Rfam
- Entry for SNORA11 at snoRNABase
- HGNC page for Small nucleolar RNA SNORA11
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