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Small nucleolar RNA SNORD78

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Small nucleolar RNA SNORD78
Identifiers
SymbolSNORD78
Alt. SymbolssnoU78
RfamRF00592
Other data
RNA typeGene; snRNA; snoRNA; C/D-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

SNORD78 (also known as U78) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593.[1] The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78 (protein non-coding).[2]

References

  1. ^ Tycowski, Kazimierz T.; Aab, Alar; Steitz, Joan A. (23 November 2004). "Guide RNAs with 5′ Caps and Novel Box C/D snoRNA-like Domains for Modification of snRNAs in Metazoa". Current Biology. 14 (22): 1985–1995. doi:10.1016/j.cub.2004.11.003. PMID 15556860.
  2. ^ Lestrade, Laurent; Weber, Michel J. (2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Supplement 1: Database Issue): D158–D162. doi:10.1093/nar/gkj002. PMC 1347365. PMID 16381836. CiteSeerx10.1.1.105.7552.