Indoprofen

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Indoprofen
Indoprofen.svg
Systematic (IUPAC) name
2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)
phenyl]propanoic acid
Clinical data
Legal status
  • Withdrawn
Routes Oral
Pharmacokinetic data
Bioavailability High (rapid and complete absorption)
Metabolism Glucuronidation
Half-life 2.3 hours
Excretion Renal
Identifiers
CAS number 31842-01-0
ATC code M01AE10
PubChem CID 3718
ChemSpider 3587 YesY
UNII CPE46ZU14N YesY
KEGG D04530 YesY
ChEBI CHEBI:76162
ChEMBL CHEMBL15870 YesY
Chemical data
Formula C17H15NO3 
Mol. mass 281.306 g/mol
 YesY (what is this?)  (verify)

Indoprofen is a non-steroidal anti-inflammatory drug. It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.[1]

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1][2]

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